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Variant-to-Gene-Mapping Analyses Reveal a Role for the Hypothalamus in Genetic Susceptibility to Inflammatory Bowel Disease.
Lasconi C, Pahl MC, Cousminer DL, Doege CA, Chesi A, Hodge KM, Leonard ME, Lu S, Johnson ME, Su C, Hammond RK, Pippin JA, Terry NA, Ghanem LR, Leibel RL, Wells AD, Grant SFA. Lasconi C, et al. Among authors: pippin ja. Cell Mol Gastroenterol Hepatol. 2021;11(3):667-682. doi: 10.1016/j.jcmgh.2020.10.004. Epub 2020 Oct 16. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33069917 Free PMC article.
Genome-wide association study implicates novel loci and reveals candidate effector genes for longitudinal pediatric bone accrual.
Cousminer DL, Wagley Y, Pippin JA, Elhakeem A, Way GP, Pahl MC, McCormack SE, Chesi A, Mitchell JA, Kindler JM, Baird D, Hartley A, Howe L, Kalkwarf HJ, Lappe JM, Lu S, Leonard ME, Johnson ME, Hakonarson H, Gilsanz V, Shepherd JA, Oberfield SE, Greene CS, Kelly A, Lawlor DA, Voight BF, Wells AD, Zemel BS, Hankenson KD, Grant SFA. Cousminer DL, et al. Among authors: pippin ja. Genome Biol. 2021 Jan 4;22(1):1. doi: 10.1186/s13059-020-02207-9. Genome Biol. 2021. PMID: 33397451 Free PMC article.
3D promoter architecture re-organization during iPSC-derived neuronal cell differentiation implicates target genes for neurodevelopmental disorders.
Su C, Argenziano M, Lu S, Pippin JA, Pahl MC, Leonard ME, Cousminer DL, Johnson ME, Lasconi C, Wells AD, Chesi A, Grant SFA. Su C, et al. Among authors: pippin ja. Prog Neurobiol. 2021 Jun;201:102000. doi: 10.1016/j.pneurobio.2021.102000. Epub 2021 Feb 2. Prog Neurobiol. 2021. PMID: 33545232 Free PMC article.
Cis-regulatory architecture of human ESC-derived hypothalamic neuron differentiation aids in variant-to-gene mapping of relevant complex traits.
Pahl MC, Doege CA, Hodge KM, Littleton SH, Leonard ME, Lu S, Rausch R, Pippin JA, De Rosa MC, Basak A, Bradfield JP, Hammond RK, Boehm K, Berkowitz RI, Lasconi C, Su C, Chesi A, Johnson ME, Wells AD, Voight BF, Leibel RL, Cousminer DL, Grant SFA. Pahl MC, et al. Among authors: pippin ja. Nat Commun. 2021 Nov 19;12(1):6749. doi: 10.1038/s41467-021-27001-4. Nat Commun. 2021. PMID: 34799566 Free PMC article.
38 results