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Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia.
Hewlett E, Toma M, Sullivan-Reed K, Gordo J, Sliwinski T, Tulin A, Childers WE, Skorski T. Hewlett E, et al. Among authors: tulin a. Med Chem Res. 2020 Jun;29(6):962-978. doi: 10.1007/s00044-020-02537-0. Epub 2020 Apr 19. Med Chem Res. 2020. PMID: 33071527 Free PMC article.
Allosteric PARP1 inhibitors could provide a means of overcoming this resistance. A high throughput screen performed by Tulin et al. identified 5F02 as an allosteric PARP inhibitor that acts by preventing the enzymatic activation of PARP1 by histone H4. 5F02 d …
Allosteric PARP1 inhibitors could provide a means of overcoming this resistance. A high throughput screen performed by Tuli
Re-evaluating PARP1 inhibitor in cancer.
Tulin A. Tulin A. Nat Biotechnol. 2011 Dec 8;29(12):1078-9. doi: 10.1038/nbt.2058. Nat Biotechnol. 2011. PMID: 22158356 No abstract available.
[Preparation of transgenic house flies Musca domestica].
Erist LK, Kosorukov VS, Antipova TA, Chupina IuM, Tulin AV, Lavrov SA, Bashkirov VN, Gvozdev VA, Brem G, Korochkin LI. Erist LK, et al. Among authors: tulin av. Dokl Akad Nauk. 1999 Jul;367(3):430-2. Dokl Akad Nauk. 1999. PMID: 10505260 Russian. No abstract available.
132 results