Xu H - Search Results

1

Benfotiamine and Cognitive Decline in Alzheimer's Disease: Results of a Randomized Placebo-Controlled Phase IIa Clinical Trial.

Gibson GE, Luchsinger JA, Cirio R, Chen H, Franchino-Elder J, Hirsch JA, Bettendorff L, Chen Z, Flowers SA, Gerber LM, Grandville T, Schupf N, Xu H, Stern Y, Habeck C, Jordan B, Fonzetti P. Gibson GE, et al. Among authors: xu h. J Alzheimers Dis. 2020;78(3):989-1010. doi: 10.3233/JAD-200896. J Alzheimers Dis. 2020. PMID: 33074237 Free PMC article. Clinical Trial.

2

Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease.

Huang HM, Fowler C, Xu H, Zhang H, Gibson GE. Huang HM, et al. Among authors: xu h. Neurobiol Aging. 2005 Jun;26(6):839-48. doi: 10.1016/j.neurobiolaging.2004.07.012. Neurobiol Aging. 2005. PMID: 15718042

3

Modification of endoplasmic reticulum Ca2+ stores by select oxidants produces changes reminiscent of those in cells from patients with Alzheimer disease.

Huang HM, Chen HL, Xu H, Gibson GE. Huang HM, et al. Among authors: xu h. Free Radic Biol Med. 2005 Oct 15;39(8):979-89. doi: 10.1016/j.freeradbiomed.2005.05.017. Free Radic Biol Med. 2005. PMID: 16198225

4

Changes in inflammatory processes associated with selective vulnerability following mild impairment of oxidative metabolism.

Karuppagounder SS, Shi Q, Xu H, Gibson GE. Karuppagounder SS, et al. Among authors: xu h. Neurobiol Dis. 2007 May;26(2):353-62. doi: 10.1016/j.nbd.2007.01.011. Epub 2007 Feb 8. Neurobiol Dis. 2007. PMID: 17398105 Free PMC article.

5

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease.

Karuppagounder SS, Pinto JT, Xu H, Chen HL, Beal MF, Gibson GE. Karuppagounder SS, et al. Among authors: xu h. Neurochem Int. 2009 Feb;54(2):111-8. doi: 10.1016/j.neuint.2008.10.008. Epub 2008 Nov 8. Neurochem Int. 2009. PMID: 19041676 Free PMC article.

6

Deficits in the mitochondrial enzyme α-ketoglutarate dehydrogenase lead to Alzheimer's disease-like calcium dysregulation.

Gibson GE, Chen HL, Xu H, Qiu L, Xu Z, Denton TT, Shi Q. Gibson GE, et al. Among authors: xu h, xu z. Neurobiol Aging. 2012 Jun;33(6):1121.e13-24. doi: 10.1016/j.neurobiolaging.2011.11.003. Epub 2011 Dec 14. Neurobiol Aging. 2012. PMID: 22169199 Free PMC article.

7

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy.

Tapias V, Jainuddin S, Ahuja M, Stack C, Elipenahli C, Vignisse J, Gerges M, Starkova N, Xu H, Starkov AA, Bettendorff L, Hushpulian DM, Smirnova NA, Gazaryan IG, Kaidery NA, Wakade S, Calingasan NY, Thomas B, Gibson GE, Dumont M, Beal MF. Tapias V, et al. Among authors: xu h. Hum Mol Genet. 2018 Aug 15;27(16):2874-2892. doi: 10.1093/hmg/ddy201. Hum Mol Genet. 2018. PMID: 29860433 Free PMC article.

8

Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease.

Shi Q, Xu H, Kleinman WA, Gibson GE. Shi Q, et al. Among authors: xu h. Biochim Biophys Acta. 2008 Apr;1782(4):229-38. doi: 10.1016/j.bbadis.2007.12.008. Epub 2007 Dec 31. Biochim Biophys Acta. 2008. PMID: 18206986 Free PMC article.

9

The human brain acetylome reveals that decreased acetylation of mitochondrial proteins associates with Alzheimer's disease.

Sun L, Bhawal R, Xu H, Chen H, Anderson ET, Haroutunian V, Cross AC, Zhang S, Gibson GE. Sun L, et al. Among authors: xu h. J Neurochem. 2021 Jul;158(2):282-296. doi: 10.1111/jnc.15377. Epub 2021 May 12. J Neurochem. 2021. PMID: 33905124 Free article.

10

Reduction in the E2k subunit of the alpha-ketoglutarate dehydrogenase complex has effects independent of complex activity.

Shi Q, Chen HL, Xu H, Gibson GE. Shi Q, et al. Among authors: xu h. J Biol Chem. 2005 Mar 25;280(12):10888-96. doi: 10.1074/jbc.M409064200. Epub 2005 Jan 12. J Biol Chem. 2005. PMID: 15649899 Free article.

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