Peng Y - Search Results

1

Deficient Endoplasmic Reticulum Acetyl-CoA Import in Pancreatic Acinar Cells Leads to Chronic Pancreatitis.

Cooley MM, Thomas DDH, Deans K, Peng Y, Lugea A, Pandol SJ, Puglielli L, Groblewski GE. Cooley MM, et al. Among authors: peng y. Cell Mol Gastroenterol Hepatol. 2021;11(3):725-738. doi: 10.1016/j.jcmgh.2020.10.008. Epub 2020 Oct 17. Cell Mol Gastroenterol Hepatol. 2021. PMID: 33080365 Free PMC article.

2

Deficient import of acetyl-CoA into the ER lumen causes neurodegeneration and propensity to infections, inflammation, and cancer.

Peng Y, Li M, Clarkson BD, Pehar M, Lao PJ, Hillmer AT, Barnhart TE, Christian BT, Mitchell HA, Bendlin BB, Sandor M, Puglielli L. Peng Y, et al. J Neurosci. 2014 May 14;34(20):6772-89. doi: 10.1523/JNEUROSCI.0077-14.2014. J Neurosci. 2014. PMID: 24828632 Free PMC article.

3

Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse.

Peng Y, Kim MJ, Hullinger R, O'Riordan KJ, Burger C, Pehar M, Puglielli L. Peng Y, et al. Brain. 2016 Mar;139(Pt 3):937-52. doi: 10.1093/brain/awv385. Epub 2016 Jan 19. Brain. 2016. PMID: 26787453 Free PMC article.

4

Nϵ-lysine acetylation in the lumen of the endoplasmic reticulum: A way to regulate autophagy and maintain protein homeostasis in the secretory pathway.

Peng Y, Puglielli L. Peng Y, et al. Autophagy. 2016 Jun 2;12(6):1051-2. doi: 10.1080/15548627.2016.1164369. Epub 2016 Apr 28. Autophagy. 2016. PMID: 27124586 Free PMC article.

5

Increased expression of AT-1/SLC33A1 causes an autistic-like phenotype in mice by affecting dendritic branching and spine formation.

Hullinger R, Li M, Wang J, Peng Y, Dowell JA, Bomba-Warczak E, Mitchell HA, Burger C, Chapman ER, Denu JM, Li L, Puglielli L. Hullinger R, et al. Among authors: peng y. J Exp Med. 2016 Jun 27;213(7):1267-84. doi: 10.1084/jem.20151776. Epub 2016 May 30. J Exp Med. 2016. PMID: 27242167 Free PMC article.

6

Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.

Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L. Peng Y, et al. Aging Cell. 2018 Oct;17(5):e12820. doi: 10.1111/acel.12820. Epub 2018 Jul 27. Aging Cell. 2018. PMID: 30051577 Free PMC article.

7

Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk.

Dieterich IA, Lawton AJ, Peng Y, Yu Q, Rhoads TW, Overmyer KA, Cui Y, Armstrong EA, Howell PR, Burhans MS, Li L, Denu JM, Coon JJ, Anderson RM, Puglielli L. Dieterich IA, et al. Among authors: peng y. Nat Commun. 2019 Sep 2;10(1):3929. doi: 10.1038/s41467-019-11945-9. Nat Commun. 2019. PMID: 31477734 Free PMC article.

8

ATG9A regulates proteostasis through reticulophagy receptors FAM134B and SEC62 and folding chaperones CALR and HSPB1.

Sheehan BK, Orefice NS, Peng Y, Shapiro SL, Puglielli L. Sheehan BK, et al. Among authors: peng y. iScience. 2021 Mar 16;24(4):102315. doi: 10.1016/j.isci.2021.102315. eCollection 2021 Apr 23. iScience. 2021. PMID: 33870132 Free PMC article.

9

ATase inhibition rescues age-associated proteotoxicity of the secretory pathway.

Murie M, Peng Y, Rigby MJ, Dieterich IA, Farrugia MA, Endresen A, Bhattacharyya A, Puglielli L. Murie M, et al. Among authors: peng y. Commun Biol. 2022 Feb 25;5(1):173. doi: 10.1038/s42003-022-03118-0. Commun Biol. 2022. PMID: 35217767 Free PMC article.

10

Spatial selectivity of ATase inhibition in mouse models of Charcot-Marie-Tooth disease.

Fernandez-Fuente G, Farrugia MA, Peng Y, Schneider A, Svaren J, Puglielli L. Fernandez-Fuente G, et al. Among authors: peng y. Brain Commun. 2024 Jul 9;6(4):fcae232. doi: 10.1093/braincomms/fcae232. eCollection 2024. Brain Commun. 2024. PMID: 39035418 Free PMC article.

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