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Page 1
Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
McDonald G, Chubukov V, Coco J, Truskowski K, Narayanaswamy R, Choe S, Steadman M, Artin E, Padyana AK, Jin L, Ronseaux S, Locuson C, Fan ZP, Erdmann T, Mann A, Hayes S, Fletcher M, Nellore K, Rao SS, Subramanya H, Reddy KS, Panigrahi SK, Antony T, Gopinath S, Sui Z, Nagaraja N, Dang L, Lenz G, Hurov J, Biller SA, Murtie J, Marks KM, Ulanet DB. McDonald G, et al. Among authors: coco j. Mol Cancer Ther. 2020 Dec;19(12):2502-2515. doi: 10.1158/1535-7163.MCT-20-0550. Epub 2020 Oct 20. Mol Cancer Ther. 2020. PMID: 33082276
Hsp90 (heat shock protein 90) inhibitor occupancy is a direct determinant of client protein degradation and tumor growth arrest in vivo.
Tillotson B, Slocum K, Coco J, Whitebread N, Thomas B, West KA, MacDougall J, Ge J, Ali JA, Palombella VJ, Normant E, Adams J, Fritz CC. Tillotson B, et al. Among authors: coco j. J Biol Chem. 2010 Dec 17;285(51):39835-43. doi: 10.1074/jbc.M110.141580. Epub 2010 Oct 12. J Biol Chem. 2010. PMID: 20940293 Free PMC article.
Addressing ethical issues in healthcare artificial intelligence using a lifecycle-informed process.
Collins BX, Bélisle-Pipon JC, Evans BJ, Ferryman K, Jiang X, Nebeker C, Novak L, Roberts K, Were M, Yin Z, Ravitsky V, Coco J, Hendricks-Sturrup R, Williams I, Clayton EW, Malin BA; Bridge2AI Ethics and Trustworthy AI Working Group. Collins BX, et al. Among authors: coco j. JAMIA Open. 2024 Nov 15;7(4):ooae108. doi: 10.1093/jamiaopen/ooae108. eCollection 2024 Dec. JAMIA Open. 2024. PMID: 39553826 Free PMC article.
Developing Ethics and Equity Principles, Terms, and Engagement Tools to Advance Health Equity and Researcher Diversity in AI and Machine Learning: Modified Delphi Approach.
Hendricks-Sturrup R, Simmons M, Anders S, Aneni K, Wright Clayton E, Coco J, Collins B, Heitman E, Hussain S, Joshi K, Lemieux J, Lovett Novak L, Rubin DJ, Shanker A, Washington T, Waters G, Webb Harris J, Yin R, Wagner T, Yin Z, Malin B. Hendricks-Sturrup R, et al. Among authors: coco j. JMIR AI. 2023 Dec 6;2:e52888. doi: 10.2196/52888. JMIR AI. 2023. PMID: 38875540 Free PMC article.
Spondias sp: Shedding Light on Its Vast Pharmaceutical Potential.
Santos ÉMD, Ataide JA, Coco JC, Fava ALM, Silvério LAL, Sueiro AC, Silva JRA, Lopes AM, Paiva-Santos AC, Mazzola PG. Santos ÉMD, et al. Among authors: coco jc. Molecules. 2023 Feb 16;28(4):1862. doi: 10.3390/molecules28041862. Molecules. 2023. PMID: 36838849 Free PMC article. Review.
Co-Encapsulation of Drugs for Topical Application-A Review.
Ataide JA, Coco JC, Dos Santos ÉM, Beraldo-Araujo V, Silva JRA, de Castro KC, Lopes AM, Filipczak N, Yalamarty SSK, Torchilin VP, Mazzola PG. Ataide JA, et al. Among authors: coco jc. Molecules. 2023 Feb 2;28(3):1449. doi: 10.3390/molecules28031449. Molecules. 2023. PMID: 36771111 Free PMC article. Review.
Pluronic® triblock copolymer-based nanoformulations for cancer therapy: A 10-year overview.
de Castro KC, Coco JC, Dos Santos ÉM, Ataide JA, Martinez RM, do Nascimento MHM, Prata J, da Fonte PRML, Severino P, Mazzola PG, Baby AR, Souto EB, de Araujo DR, Lopes AM. de Castro KC, et al. Among authors: coco jc. J Control Release. 2023 Jan;353:802-822. doi: 10.1016/j.jconrel.2022.12.017. Epub 2022 Dec 17. J Control Release. 2023. PMID: 36521691 Review.
39 results