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Dual Recombining-out System for Spatiotemporal Gene Expression in C. elegans.
Ge MH, Wang W, Wu TH, Wen X, Al-Sheikh U, Chen LL, Yin SW, Wu JJ, Huang JH, He QQ, Liu H, Li R, Wang PZ, Wu ZX. Ge MH, et al. Among authors: wen x. iScience. 2020 Sep 15;23(10):101567. doi: 10.1016/j.isci.2020.101567. eCollection 2020 Oct 23. iScience. 2020. PMID: 33083734 Free PMC article.
Ligand recognition and allosteric regulation of DRD1-Gs signaling complexes.
Xiao P, Yan W, Gou L, Zhong YN, Kong L, Wu C, Wen X, Yuan Y, Cao S, Qu C, Yang X, Yang CC, Xia A, Hu Z, Zhang Q, He YH, Zhang DL, Zhang C, Hou GH, Liu H, Zhu L, Fu P, Yang S, Rosenbaum DM, Sun JP, Du Y, Zhang L, Yu X, Shao Z. Xiao P, et al. Among authors: wen x. Cell. 2021 Feb 18;184(4):943-956.e18. doi: 10.1016/j.cell.2021.01.028. Epub 2021 Feb 10. Cell. 2021. PMID: 33571432 Free PMC article.
Structures of the glucocorticoid-bound adhesion receptor GPR97-Go complex.
Ping YQ, Mao C, Xiao P, Zhao RJ, Jiang Y, Yang Z, An WT, Shen DD, Yang F, Zhang H, Qu C, Shen Q, Tian C, Li ZJ, Li S, Wang GY, Tao X, Wen X, Zhong YN, Yang J, Yi F, Yu X, Xu HE, Zhang Y, Sun JP. Ping YQ, et al. Among authors: wen x. Nature. 2021 Jan;589(7843):620-626. doi: 10.1038/s41586-020-03083-w. Epub 2021 Jan 6. Nature. 2021. PMID: 33408414
Single hormone or synthetic agonist induces Gs/Gi coupling selectivity of EP receptors via distinct binding modes and propagating paths.
Huang SM, Xiong MY, Liu L, Mu J, Wang MW, Jia YL, Cai K, Tie L, Zhang C, Cao S, Wen X, Wang JL, Guo SC, Li Y, Qu CX, He QT, Cai BY, Xue C, Gan S, Xie Y, Cong X, Yang Z, Kong W, Li S, Li Z, Xiao P, Yang F, Yu X, Guan YF, Zhang X, Liu Z, Yang BX, Du Y, Sun JP. Huang SM, et al. Among authors: wen x. Proc Natl Acad Sci U S A. 2023 Jul 25;120(30):e2216329120. doi: 10.1073/pnas.2216329120. Epub 2023 Jul 21. Proc Natl Acad Sci U S A. 2023. PMID: 37478163 Free PMC article.
Structural insights into the mechanisms of urea permeation and distinct inhibition modes of urea transporters.
Huang SM, Huang ZZ, Liu L, Xiong MY, Zhang C, Cai BY, Wang MW, Cai K, Jia YL, Wang JL, Zhang MH, Xie YH, Li M, Zhang H, Weng CH, Wen X, Li Z, Sun Y, Yi F, Yang Z, Xiao P, Yang F, Yu X, Tie L, Yang BX, Sun JP. Huang SM, et al. Among authors: wen x. Nat Commun. 2024 Nov 26;15(1):10226. doi: 10.1038/s41467-024-54305-y. Nat Commun. 2024. PMID: 39587082 Free PMC article.
DT7 peptide-modified lecithin nanoparticles co-loaded with γ-secretase inhibitor and dexamethasone efficiently inhibit T-cell acute lymphoblastic leukemia and reduce gastrointestinal toxicity.
Zhou Y, Guan L, Li W, Jia R, Jia L, Zhang Y, Wen X, Meng S, Ma D, Zhang N, Ji M, Liu Y, Ji C. Zhou Y, et al. Among authors: wen x. Cancer Lett. 2022 May 1;533:215608. doi: 10.1016/j.canlet.2022.215608. Epub 2022 Feb 28. Cancer Lett. 2022. PMID: 35240234 Free article.
Tethered peptide activation mechanism of the adhesion GPCRs ADGRG2 and ADGRG4.
Xiao P, Guo S, Wen X, He QT, Lin H, Huang SM, Gou L, Zhang C, Yang Z, Zhong YN, Yang CC, Li Y, Gong Z, Tao XN, Yang ZS, Lu Y, Li SL, He JY, Wang C, Zhang L, Kong L, Sun JP, Yu X. Xiao P, et al. Among authors: wen x. Nature. 2022 Apr;604(7907):771-778. doi: 10.1038/s41586-022-04590-8. Epub 2022 Apr 13. Nature. 2022. PMID: 35418677
7,535 results