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Gene therapy augments the efficacy of hematopoietic cell transplantation and fully corrects mucopolysaccharidosis type I phenotype in the mouse model.
Visigalli I, Delai S, Politi LS, Di Domenico C, Cerri F, Mrak E, D'Isa R, Ungaro D, Stok M, Sanvito F, Mariani E, Staszewsky L, Godi C, Russo I, Cecere F, Del Carro U, Rubinacci A, Brambilla R, Quattrini A, Di Natale P, Ponder K, Naldini L, Biffi A. Visigalli I, et al. Among authors: politi ls. Blood. 2010 Dec 9;116(24):5130-9. doi: 10.1182/blood-2010-04-278234. Epub 2010 Sep 16. Blood. 2010. PMID: 20847202 Free PMC article.
Epidermal growth factor receptor expression identifies functionally and molecularly distinct tumor-initiating cells in human glioblastoma multiforme and is required for gliomagenesis.
Mazzoleni S, Politi LS, Pala M, Cominelli M, Franzin A, Sergi Sergi L, Falini A, De Palma M, Bulfone A, Poliani PL, Galli R. Mazzoleni S, et al. Among authors: politi ls. Cancer Res. 2010 Oct 1;70(19):7500-13. doi: 10.1158/0008-5472.CAN-10-2353. Epub 2010 Sep 21. Cancer Res. 2010. PMID: 20858720 Free article.
Gene signatures associated with mouse postnatal hindbrain neural stem cells and medulloblastoma cancer stem cells identify novel molecular mediators and predict human medulloblastoma molecular classification.
Corno D, Pala M, Cominelli M, Cipelletti B, Leto K, Croci L, Barili V, Brandalise F, Melzi R, Di Gregorio A, Sergi LS, Politi LS, Piemonti L, Bulfone A, Rossi P, Rossi F, Consalez GG, Poliani PL, Galli R. Corno D, et al. Among authors: politi ls. Cancer Discov. 2012 Jun;2(6):554-68. doi: 10.1158/2159-8290.CD-11-0199. Epub 2012 May 3. Cancer Discov. 2012. PMID: 22628409 Free article.
Brain conditioning is instrumental for successful microglia reconstitution following hematopoietic stem cell transplantation.
Capotondo A, Milazzo R, Politi LS, Quattrini A, Palini A, Plati T, Merella S, Nonis A, di Serio C, Montini E, Naldini L, Biffi A. Capotondo A, et al. Among authors: politi ls. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):15018-23. doi: 10.1073/pnas.1205858109. Epub 2012 Aug 23. Proc Natl Acad Sci U S A. 2012. PMID: 22923692 Free PMC article.
140 results