Doonan J - Search Results

1

Development of Acanthocheilonema viteae in Meriones shawi: Absence of microfilariae and production of active ES-62.

Lumb FE, Doonan J, Corbet M, Pineda MA, M Harnett M, Harnett W. Lumb FE, et al. Among authors: doonan j. Parasite Immunol. 2021 Mar;43(3):e12803. doi: 10.1111/pim.12803. Epub 2020 Nov 10. Parasite Immunol. 2021. PMID: 33091157 Free PMC article.

2

Testing small molecule analogues of the Acanthocheilonema viteae immunomodulator ES-62 against clinically relevant allergens.

Janicova L, Rzepecka J, Rodgers DT, Doonan J, Bell KS, Lumb FE, Suckling CJ, Harnett MM, Harnett W. Janicova L, et al. Among authors: doonan j. Parasite Immunol. 2016 Jun;38(6):340-51. doi: 10.1111/pim.12322. Parasite Immunol. 2016. PMID: 27059010 Free PMC article.

3

Dendritic cells provide a therapeutic target for synthetic small molecule analogues of the parasitic worm product, ES-62.

Lumb FE, Doonan J, Bell KS, Pineda MA, Corbet M, Suckling CJ, Harnett MM, Harnett W. Lumb FE, et al. Among authors: doonan j. Sci Rep. 2017 May 10;7(1):1704. doi: 10.1038/s41598-017-01651-1. Sci Rep. 2017. PMID: 28490801 Free PMC article.

4

Protection Against Arthritis by the Parasitic Worm Product ES-62, and Its Drug-Like Small Molecule Analogues, Is Associated With Inhibition of Osteoclastogenesis.

Doonan J, Lumb FE, Pineda MA, Tarafdar A, Crowe J, Khan AM, Suckling CJ, Harnett MM, Harnett W. Doonan J, et al. Front Immunol. 2018 May 14;9:1016. doi: 10.3389/fimmu.2018.01016. eCollection 2018. Front Immunol. 2018. PMID: 29867986 Free PMC article.

5

Failure of the Anti-Inflammatory Parasitic Worm Product ES-62 to Provide Protection in Mouse Models of Type I Diabetes, Multiple Sclerosis, and Inflammatory Bowel Disease.

Doonan J, Thomas D, Wong MH, Ramage HJ, Al-Riyami L, Lumb FE, Bell KS, Fairlie-Clarke KJ, Suckling CJ, Michelsen KS, Jiang HR, Cooke A, Harnett MM, Harnett W. Doonan J, et al. Molecules. 2018 Oct 17;23(10):2669. doi: 10.3390/molecules23102669. Molecules. 2018. PMID: 30336585 Free PMC article.

6

The parasitic worm product ES-62 normalises the gut microbiota bone marrow axis in inflammatory arthritis.

Doonan J, Tarafdar A, Pineda MA, Lumb FE, Crowe J, Khan AM, Hoskisson PA, Harnett MM, Harnett W. Doonan J, et al. Nat Commun. 2019 Apr 5;10(1):1554. doi: 10.1038/s41467-019-09361-0. Nat Commun. 2019. PMID: 30952846 Free PMC article.

7

Site-specific glycoproteomic characterization of ES-62: The major secreted product of the parasitic worm Acanthocheilonema viteae.

North SJ, Botchway K, Doonan J, Lumb FE, Dell A, Harnett W, Haslam SM. North SJ, et al. Among authors: doonan j. Glycobiology. 2019 Jul 19;29(8):562-571. doi: 10.1093/glycob/cwz035. Glycobiology. 2019. PMID: 31094418 Free PMC article.

8

Synthetic small molecule analogues of the immunomodulatory Acanthocheilonema viteae product ES-62 promote metabolic homeostasis during obesity in a mouse model.

Lumb FE, Crowe J, Doonan J, Suckling CJ, Selman C, Harnett MM, Harnett W. Lumb FE, et al. Among authors: doonan j. Mol Biochem Parasitol. 2019 Dec;234:111232. doi: 10.1016/j.molbiopara.2019.111232. Epub 2019 Oct 18. Mol Biochem Parasitol. 2019. PMID: 31634505 Free article.

9

The parasitic worm product ES-62 promotes health- and life-span in a high calorie diet-accelerated mouse model of ageing.

Crowe J, Lumb FE, Doonan J, Broussard M, Tarafdar A, Pineda MA, Landabaso C, Mulvey L, Hoskisson PA, Babayan SA, Selman C, Harnett W, Harnett MM. Crowe J, et al. Among authors: doonan j. PLoS Pathog. 2020 Mar 12;16(3):e1008391. doi: 10.1371/journal.ppat.1008391. eCollection 2020 Mar. PLoS Pathog. 2020. PMID: 32163524 Free PMC article.

10

The parasitic worm product ES-62 protects the osteoimmunology axis in a mouse model of obesity-accelerated ageing.

Harnett MM, Doonan J, Lumb FE, Crowe J, Damink RO, Buitrago G, Duncombe-Moore J, Wilkinson DI, Suckling CJ, Selman C, Harnett W. Harnett MM, et al. Among authors: doonan j. Front Immunol. 2022 Aug 29;13:953053. doi: 10.3389/fimmu.2022.953053. eCollection 2022. Front Immunol. 2022. PMID: 36105811 Free PMC article.

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