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Pharmacophore-based virtual screening, synthesis, biological evaluation, and molecular docking study of novel pyrrolizines bearing urea/thiourea moieties with potential cytotoxicity and CDK inhibitory activities.
Shawky AM, Ibrahim NA, Abourehab MAS, Abdalla AN, Gouda AM. Shawky AM, et al. Among authors: abdalla an. J Enzyme Inhib Med Chem. 2021 Dec;36(1):15-33. doi: 10.1080/14756366.2020.1837124. J Enzyme Inhib Med Chem. 2021. PMID: 33103497 Free PMC article.
Synthesis, cytotoxic evaluation, and molecular docking studies of novel quinazoline derivatives with benzenesulfonamide and anilide tails: Dual inhibitors of EGFR/HER2.
Alkahtani HM, Abdalla AN, Obaidullah AJ, Alanazi MM, Almehizia AA, Alanazi MG, Ahmed AY, Alwassil OI, Darwish HW, Abdel-Aziz AA, El-Azab AS. Alkahtani HM, et al. Among authors: abdalla an. Bioorg Chem. 2020 Jan;95:103461. doi: 10.1016/j.bioorg.2019.103461. Epub 2019 Dec 3. Bioorg Chem. 2020. PMID: 31838290
122 results