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Page 1
Protocol for Application, Standardization and Validation of the Forskolin-Induced Swelling Assay in Cystic Fibrosis Human Colon Organoids.
Vonk AM, van Mourik P, Ramalho AS, Silva IAL, Statia M, Kruisselbrink E, Suen SWF, Dekkers JF, Vleggaar FP, Houwen RHJ, Mullenders J, Boj SF, Vries R, Amaral MD, de Boeck K, van der Ent CK, Beekman JM. Vonk AM, et al. Among authors: vleggaar fp. STAR Protoc. 2020 Jun 3;1(1):100019. doi: 10.1016/j.xpro.2020.100019. eCollection 2020 Jun 19. STAR Protoc. 2020. PMID: 33111074 Free PMC article.
Characterizing responses to CFTR-modulating drugs using rectal organoids derived from subjects with cystic fibrosis.
Dekkers JF, Berkers G, Kruisselbrink E, Vonk A, de Jonge HR, Janssens HM, Bronsveld I, van de Graaf EA, Nieuwenhuis EE, Houwen RH, Vleggaar FP, Escher JC, de Rijke YB, Majoor CJ, Heijerman HG, de Winter-de Groot KM, Clevers H, van der Ent CK, Beekman JM. Dekkers JF, et al. Among authors: vleggaar fp. Sci Transl Med. 2016 Jun 22;8(344):344ra84. doi: 10.1126/scitranslmed.aad8278. Sci Transl Med. 2016. PMID: 27334259
Forskolin-induced swelling of intestinal organoids correlates with disease severity in adults with cystic fibrosis and homozygous F508del mutations.
de Winter-de Groot KM, Berkers G, Marck-van der Wilt REP, van der Meer R, Vonk A, Dekkers JF, Geerdink M, Michel S, Kruisselbrink E, Vries R, Clevers H, Vleggaar FP, Elias SG, Heijerman HGM, van der Ent CK, Beekman JM. de Winter-de Groot KM, et al. Among authors: vleggaar fp. J Cyst Fibros. 2020 Jul;19(4):614-619. doi: 10.1016/j.jcf.2019.10.022. Epub 2019 Nov 15. J Cyst Fibros. 2020. PMID: 31735562 Free article.
Centralized intestinal organoid generation is a feasible and safe approach for personalized medicine as demonstrated in the HIT-CF Europe Organoid Study.
Bierlaagh MC, van Mourik P, Vonk AM, Pott J, Muilwijk D, Berkers G, Aalbers BL, Vleggaar FP, Michel S, Boj SF, Vries RGJ, Beekman JM, van der Ent CK; HIT-CF organoid study group. Bierlaagh MC, et al. Among authors: vleggaar fp. J Cyst Fibros. 2024 Jul;23(4):703-706. doi: 10.1016/j.jcf.2024.04.016. Epub 2024 May 18. J Cyst Fibros. 2024. PMID: 38763840 Free article.
Multicentre prospective evaluation of real-time optical diagnosis of T1 colorectal cancer in large non-pedunculated colorectal polyps using narrow band imaging (the OPTICAL study).
Backes Y, Schwartz MP, Ter Borg F, Wolfhagen FHJ, Groen JN, de Vos Tot Nederveen Cappel WH, van Bergeijk J, Geesing JMJ, Spanier BWM, Didden P, Vleggaar FP, Lacle MM, Elias SG, Moons LMG; Dutch T1 CRC Working Group. Backes Y, et al. Among authors: vleggaar fp. Gut. 2019 Feb;68(2):271-279. doi: 10.1136/gutjnl-2017-314723. Epub 2018 Jan 3. Gut. 2019. PMID: 29298873
Tumor Seeding During Colonoscopy as a Possible Cause for Metachronous Colorectal Cancer.
Backes Y, Seerden TCJ, van Gestel RSFE, Kranenburg O, Ubink I, Schiffelers RM, van Straten D, van der Capellen MS, van de Weerd S, de Leng WWJ, Siersema PD, Offerhaus GJA, Morsink FH, Ramphal W, Terhaar Sive Droste J, van Lent AUG, Geesing JMJ, Vleggaar FP, Elias SG, Lacle MM, Moons LMG. Backes Y, et al. Among authors: vleggaar fp. Gastroenterology. 2019 Nov;157(5):1222-1232.e4. doi: 10.1053/j.gastro.2019.07.062. Epub 2019 Aug 13. Gastroenterology. 2019. PMID: 31419435
How to drain the gallbladder: that is the question.
Bogte A, Vleggaar FP. Bogte A, et al. Among authors: vleggaar fp. Endoscopy. 2020 Feb;52(2):88-89. doi: 10.1055/a-1082-3687. Epub 2020 Jan 28. Endoscopy. 2020. PMID: 31991467 No abstract available.
Histologic Factors Associated With Need for Surgery in Patients With Pedunculated T1 Colorectal Carcinomas.
Backes Y, Elias SG, Groen JN, Schwartz MP, Wolfhagen FHJ, Geesing JMJ, Ter Borg F, van Bergeijk J, Spanier BWM, de Vos Tot Nederveen Cappel WH, Kessels K, Seldenrijk CA, Raicu MG, Drillenburg P, Milne AN, Kerkhof M, Seerden TCJ, Siersema PD, Vleggaar FP, Offerhaus GJA, Lacle MM, Moons LMG; Dutch T1 CRC Working Group. Backes Y, et al. Among authors: vleggaar fp. Gastroenterology. 2018 May;154(6):1647-1659. doi: 10.1053/j.gastro.2018.01.023. Epub 2018 Jan 31. Gastroenterology. 2018. PMID: 29366842
Pedunculated Morphology of T1 Colorectal Tumors Associates With Reduced Risk of Adverse Outcome.
Kessels K, Backes Y, Elias SG, van den Blink A, Offerhaus GJA, van Bergeijk JD, Groen JN, Seerden TCJ, Schwartz MP, de Vos Tot Nederveen Cappel WH, Spanier BWM, Geesing JMJ, Kerkhof M, Siersema PD, Didden P, Boonstra JJ, Herrero LA, Wolfhagen FHJ, Ter Borg F, van Lent AU, Terhaar Sive Droste JS, Hazen WL, Schrauwen RWM, Vleggaar FP, Laclé MM, Moons LMG; Dutch T1 Colorectal Cancer Working Group. Kessels K, et al. Among authors: vleggaar fp. Clin Gastroenterol Hepatol. 2019 May;17(6):1112-1120.e1. doi: 10.1016/j.cgh.2018.08.041. Epub 2018 Aug 18. Clin Gastroenterol Hepatol. 2019. PMID: 30130623
217 results