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Unfractionated heparin inhibits live wild type SARS-CoV-2 cell infectivity at therapeutically relevant concentrations.
Tree JA, Turnbull JE, Buttigieg KR, Elmore MJ, Coombes N, Hogwood J, Mycroft-West CJ, Lima MA, Skidmore MA, Karlsson R, Chen YH, Yang Z, Spalluto CM, Staples KJ, Yates EA, Gray E, Singh D, Wilkinson T, Page CP, Carroll MW. Tree JA, et al. Among authors: gray e. Br J Pharmacol. 2021 Feb;178(3):626-635. doi: 10.1111/bph.15304. Epub 2020 Dec 14. Br J Pharmacol. 2021. PMID: 33125711 Free PMC article.
Pharmacology of Heparin and Related Drugs.
Mulloy B, Hogwood J, Gray E, Lever R, Page CP. Mulloy B, et al. Among authors: gray e. Pharmacol Rev. 2016 Jan;68(1):76-141. doi: 10.1124/pr.115.011247. Pharmacol Rev. 2016. PMID: 26672027 Review.
Animal models of mechanisms of SARS-CoV-2 infection and COVID-19 pathology.
Cleary SJ, Pitchford SC, Amison RT, Carrington R, Robaina Cabrera CL, Magnen M, Looney MR, Gray E, Page CP. Cleary SJ, et al. Among authors: gray e. Br J Pharmacol. 2020 Nov;177(21):4851-4865. doi: 10.1111/bph.15143. Epub 2020 Jul 19. Br J Pharmacol. 2020. PMID: 32462701 Free PMC article. Review.
Biochemical and functional characterization of glycosaminoglycans released from degranulating rat peritoneal mast cells: Insights into the physiological role of endogenous heparin.
Lever R, Smailbegovic A, Riffo-Vasquez Y, Gray E, Hogwood J, Francis SM, Richardson NV, Page CP, Mulloy B. Lever R, et al. Among authors: gray e. Pulm Pharmacol Ther. 2016 Dec;41:96-102. doi: 10.1016/j.pupt.2016.11.002. Epub 2016 Nov 3. Pulm Pharmacol Ther. 2016. PMID: 27816772
1,380 results