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Page 1
Rapamycin Extends Life Span in ApcMin/+ Colon Cancer FAP Model.
Parihar M, Dodds SG, Hubbard G, Javors MA, Strong R, Hasty P, Sharp ZD. Parihar M, et al. Among authors: sharp zd. Clin Colorectal Cancer. 2021 Mar;20(1):e61-e70. doi: 10.1016/j.clcc.2020.08.006. Epub 2020 Sep 15. Clin Colorectal Cancer. 2021. PMID: 33132009 Free PMC article.
Rapamycin extends life span of Rb1+/- mice by inhibiting neuroendocrine tumors.
Livi CB, Hardman RL, Christy BA, Dodds SG, Jones D, Williams C, Strong R, Bokov A, Javors MA, Ikeno Y, Hubbard G, Hasty P, Sharp ZD. Livi CB, et al. Among authors: sharp zd. Aging (Albany NY). 2013 Feb;5(2):100-10. doi: 10.18632/aging.100533. Aging (Albany NY). 2013. PMID: 23454836 Free PMC article.
eRapa restores a normal life span in a FAP mouse model.
Hasty P, Livi CB, Dodds SG, Jones D, Strong R, Javors M, Fischer KE, Sloane L, Murthy K, Hubbard G, Sun L, Hurez V, Curiel TJ, Sharp ZD. Hasty P, et al. Among authors: sharp zd. Cancer Prev Res (Phila). 2014 Jan;7(1):169-78. doi: 10.1158/1940-6207.CAPR-13-0299. Epub 2013 Nov 26. Cancer Prev Res (Phila). 2014. PMID: 24282255 Free PMC article.
Use of Transgenic Mice in Aging Research.
Richardson A, Heydari AR, Morgan WW, Nelson JF, Sharp ZD, Walter CA. Richardson A, et al. Among authors: sharp zd. ILAR J. 1997;38(3):125-136. ILAR J. 1997. PMID: 11528054 No abstract available.
p53 and rapamycin are additive.
Christy B, Demaria M, Campisi J, Huang J, Jones D, Dodds SG, Williams C, Hubbard G, Livi CB, Gao X, Weintraub S, Curiel T, Sharp ZD, Hasty P. Christy B, et al. Among authors: sharp zd. Oncotarget. 2015 Jun 30;6(18):15802-13. doi: 10.18632/oncotarget.4602. Oncotarget. 2015. PMID: 26158292 Free PMC article.
Rapamycin Prevents Surgery-Induced Immune Dysfunction in Patients with Bladder Cancer.
Svatek RS, Ji N, de Leon E, Mukherjee NZ, Kabra A, Hurez V, Nicolas M, Michalek JE, Javors M, Wheeler K, Sharp ZD, Livi CB, Shu ZJ, Henkes D, Curiel TJ. Svatek RS, et al. Among authors: sharp zd. Cancer Immunol Res. 2019 Mar;7(3):466-475. doi: 10.1158/2326-6066.CIR-18-0336. Epub 2018 Dec 18. Cancer Immunol Res. 2019. PMID: 30563829 Free PMC article. Clinical Trial.
Adaptations to chronic rapamycin in mice.
Dodds SG, Livi CB, Parihar M, Hsu HK, Benavides AD, Morris J, Javors M, Strong R, Christy B, Hasty P, Sharp ZD. Dodds SG, et al. Among authors: sharp zd. Pathobiol Aging Age Relat Dis. 2016 May 27;6:31688. doi: 10.3402/pba.v6.31688. eCollection 2016. Pathobiol Aging Age Relat Dis. 2016. PMID: 27237224 Free PMC article.
95 results