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Congeners Derived from Microtubule-Active Phenylpyrimidines Produce a Potent and Long-Lasting Paralysis of Schistosoma mansoni In Vitro.
Monti L, Cornec AS, Oukoloff K, Kovalevich J, Prijs K, Alle T, Brunden KR, Smith AB 3rd, El-Sakkary N, Liu LJ, Syed A, Skinner DE, Ballatore C, Caffrey CR. Monti L, et al. Among authors: caffrey cr. ACS Infect Dis. 2021 May 14;7(5):1089-1103. doi: 10.1021/acsinfecdis.0c00508. Epub 2020 Oct 31. ACS Infect Dis. 2021. PMID: 33135408 Free PMC article.
Prolyl Oligopeptidase from the Blood Fluke Schistosoma mansoni: From Functional Analysis to Anti-schistosomal Inhibitors.
Fajtová P, Štefanić S, Hradilek M, Dvořák J, Vondrášek J, Jílková A, Ulrychová L, McKerrow JH, Caffrey CR, Mareš M, Horn M. Fajtová P, et al. Among authors: caffrey cr. PLoS Negl Trop Dis. 2015 Jun 3;9(6):e0003827. doi: 10.1371/journal.pntd.0003827. eCollection 2015. PLoS Negl Trop Dis. 2015. PMID: 26039195 Free PMC article.
Structure-Bioactivity Relationship for Benzimidazole Thiophene Inhibitors of Polo-Like Kinase 1 (PLK1), a Potential Drug Target in Schistosoma mansoni.
Long T, Neitz RJ, Beasley R, Kalyanaraman C, Suzuki BM, Jacobson MP, Dissous C, McKerrow JH, Drewry DH, Zuercher WJ, Singh R, Caffrey CR. Long T, et al. Among authors: caffrey cr. PLoS Negl Trop Dis. 2016 Jan 11;10(1):e0004356. doi: 10.1371/journal.pntd.0004356. eCollection 2016 Jan. PLoS Negl Trop Dis. 2016. PMID: 26751972 Free PMC article.
Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA Jr, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. Long T, et al. Among authors: caffrey cr. PLoS Negl Trop Dis. 2017 Jul 13;11(7):e0005680. doi: 10.1371/journal.pntd.0005680. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28704396 Free PMC article.
183 results