Parrish HL - Search Results

1

A biomimetic five-module chimeric antigen receptor (^5MCAR) designed to target and eliminate antigen-specific T cells.

Kobayashi S, Thelin MA, Parrish HL, Deshpande NR, Lee MS, Karimzadeh A, Niewczas MA, Serwold T, Kuhns MS. Kobayashi S, et al. Among authors: parrish hl. Proc Natl Acad Sci U S A. 2020 Nov 17;117(46):28950-28959. doi: 10.1073/pnas.2012495117. Epub 2020 Nov 2. Proc Natl Acad Sci U S A. 2020. PMID: 33139567 Free PMC article.

2

A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

Parrish HL, Glassman CR, Keenen MM, Deshpande NR, Bronnimann MP, Kuhns MS. Parrish HL, et al. PLoS One. 2015 Jul 6;10(7):e0132333. doi: 10.1371/journal.pone.0132333. eCollection 2015. PLoS One. 2015. PMID: 26147390 Free PMC article.

3

Self-recognition drives the preferential accumulation of promiscuous CD4(+) T-cells in aged mice.

Deshpande NR, Parrish HL, Kuhns MS. Deshpande NR, et al. Among authors: parrish hl. Elife. 2015 Jul 14;4:e05949. doi: 10.7554/eLife.05949. Elife. 2015. PMID: 26173205 Free PMC article.

4

A Mechanical Switch Couples T Cell Receptor Triggering to the Cytoplasmic Juxtamembrane Regions of CD3ζζ.

Lee MS, Glassman CR, Deshpande NR, Badgandi HB, Parrish HL, Uttamapinant C, Stawski PS, Ting AY, Kuhns MS. Lee MS, et al. Among authors: parrish hl. Immunity. 2015 Aug 18;43(2):227-39. doi: 10.1016/j.immuni.2015.06.018. Epub 2015 Jul 28. Immunity. 2015. PMID: 26231119 Free PMC article.

5

Functional evidence for TCR-intrinsic specificity for MHCII.

Parrish HL, Deshpande NR, Vasic J, Kuhns MS. Parrish HL, et al. Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3000-5. doi: 10.1073/pnas.1518499113. Epub 2016 Feb 1. Proc Natl Acad Sci U S A. 2016. PMID: 26831112 Free PMC article.

6

Correction: A Transmembrane Domain GGxxG Motif in CD4 Contributes to Its Lck-Independent Function but Does Not Mediate CD4 Dimerization.

Parrish HL, Glassman CR, Keenen MM, Deshpande NR, Bronnimann MP, Kuhns MS. Parrish HL, et al. PLoS One. 2016 Mar 1;11(3):e0150876. doi: 10.1371/journal.pone.0150876. eCollection 2016. PLoS One. 2016. PMID: 26930656 Free PMC article. No abstract available.

7

The CD4 and CD3δε Cytosolic Juxtamembrane Regions Are Proximal within a Compact TCR-CD3-pMHC-CD4 Macrocomplex.

Glassman CR, Parrish HL, Deshpande NR, Kuhns MS. Glassman CR, et al. Among authors: parrish hl. J Immunol. 2016 Jun 1;196(11):4713-22. doi: 10.4049/jimmunol.1502110. Epub 2016 May 2. J Immunol. 2016. PMID: 27183595 Free PMC article.

8

Reciprocal TCR-CD3 and CD4 Engagement of a Nucleating pMHCII Stabilizes a Functional Receptor Macrocomplex.

Glassman CR, Parrish HL, Lee MS, Kuhns MS. Glassman CR, et al. Among authors: parrish hl. Cell Rep. 2018 Jan 30;22(5):1263-1275. doi: 10.1016/j.celrep.2017.12.104. Cell Rep. 2018. PMID: 29386113 Free PMC article.

9

Enhancing and inhibitory motifs regulate CD4 activity.

Lee MS, Tuohy PJ, Kim CY, Lichauco K, Parrish HL, Van Doorslaer K, Kuhns MS. Lee MS, et al. Among authors: parrish hl. Elife. 2022 Jul 21;11:e79508. doi: 10.7554/eLife.79508. Elife. 2022. PMID: 35861317 Free PMC article.

10

The TCR Cα Domain Regulates Responses to Self-pMHC Class II.

Kim CY, Parrish HL, Kuhns MS. Kim CY, et al. Among authors: parrish hl. J Immunol. 2022 Nov 15;209(10):2033-2041. doi: 10.4049/jimmunol.2200377. J Immunol. 2022. PMID: 36426940 Free PMC article.

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