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The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.
Richard AM, Huang R, Waidyanatha S, Shinn P, Collins BJ, Thillainadarajah I, Grulke CM, Williams AJ, Lougee RR, Judson RS, Houck KA, Shobair M, Yang C, Rathman JF, Yasgar A, Fitzpatrick SC, Simeonov A, Thomas RS, Crofton KM, Paules RS, Bucher JR, Austin CP, Kavlock RJ, Tice RR. Richard AM, et al. Among authors: austin cp. Chem Res Toxicol. 2021 Feb 15;34(2):189-216. doi: 10.1021/acs.chemrestox.0c00264. Epub 2020 Nov 3. Chem Res Toxicol. 2021. PMID: 33140634 Free PMC article. Review.
Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway.
Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, Shinn P, Simeonov A, Dix DJ, Austin CP, Kavlock RJ, Tice RR, Xia M. Huang R, et al. Among authors: austin cp. Sci Rep. 2014 Jul 11;4:5664. doi: 10.1038/srep05664. Sci Rep. 2014. PMID: 25012808 Free PMC article.
Dose-response modeling of high-throughput screening data.
Parham F, Austin C, Southall N, Huang R, Tice R, Portier C. Parham F, et al. J Biomol Screen. 2009 Dec;14(10):1216-27. doi: 10.1177/1087057109349355. J Biomol Screen. 2009. PMID: 19828774 Free PMC article.
Comprehensive Analyses and Prioritization of Tox21 10K Chemicals Affecting Mitochondrial Function by in-Depth Mechanistic Studies.
Xia M, Huang R, Shi Q, Boyd WA, Zhao J, Sun N, Rice JR, Dunlap PE, Hackstadt AJ, Bridge MF, Smith MV, Dai S, Zheng W, Chu PH, Gerhold D, Witt KL, DeVito M, Freedman JH, Austin CP, Houck KA, Thomas RS, Paules RS, Tice RR, Simeonov A. Xia M, et al. Among authors: austin cp. Environ Health Perspect. 2018 Jul 26;126(7):077010. doi: 10.1289/EHP2589. eCollection 2018 Jul. Environ Health Perspect. 2018. PMID: 30059008 Free PMC article.
263 results