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The Tox21 10K Compound Library: Collaborative Chemistry Advancing Toxicology.
Richard AM, Huang R, Waidyanatha S, Shinn P, Collins BJ, Thillainadarajah I, Grulke CM, Williams AJ, Lougee RR, Judson RS, Houck KA, Shobair M, Yang C, Rathman JF, Yasgar A, Fitzpatrick SC, Simeonov A, Thomas RS, Crofton KM, Paules RS, Bucher JR, Austin CP, Kavlock RJ, Tice RR. Richard AM, et al. Among authors: huang r. Chem Res Toxicol. 2021 Feb 15;34(2):189-216. doi: 10.1021/acs.chemrestox.0c00264. Epub 2020 Nov 3. Chem Res Toxicol. 2021. PMID: 33140634 Free PMC article. Review.
Identification of clinically used drugs that activate pregnane X receptors.
Shukla SJ, Sakamuru S, Huang R, Moeller TA, Shinn P, Vanleer D, Auld DS, Austin CP, Xia M. Shukla SJ, et al. Among authors: huang r. Drug Metab Dispos. 2011 Jan;39(1):151-9. doi: 10.1124/dmd.110.035105. Epub 2010 Oct 21. Drug Metab Dispos. 2011. PMID: 20966043 Free PMC article.
A quantitative high-throughput screen identifies novel inhibitors of the interaction of thyroid receptor beta with a peptide of steroid receptor coactivator 2.
Johnson RL, Hwang JY, Arnold LA, Huang R, Wichterman J, Augustinaite I, Austin CP, Inglese J, Guy RK, Huang W. Johnson RL, et al. Among authors: huang r, huang w. J Biomol Screen. 2011 Jul;16(6):618-27. doi: 10.1177/1087057111402199. Epub 2011 Apr 11. J Biomol Screen. 2011. PMID: 21482722 Free PMC article.
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