van den Boomen DJH - Search Results

1

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

van den Boomen DJH, Sienkiewicz A, Berlin I, Jongsma MLM, van Elsland DM, Luzio JP, Neefjes JJC, Lehner PJ. van den Boomen DJH, et al. Nat Commun. 2020 Nov 3;11(1):5559. doi: 10.1038/s41467-020-19032-0. Nat Commun. 2020. PMID: 33144569 Free PMC article.

2

The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER.

Stagg HR, Thomas M, van den Boomen D, Wiertz EJ, Drabkin HA, Gemmill RM, Lehner PJ. Stagg HR, et al. J Cell Biol. 2009 Sep 7;186(5):685-92. doi: 10.1083/jcb.200906110. Epub 2009 Aug 31. J Cell Biol. 2009. PMID: 19720873 Free PMC article.

3

MHC class I molecules are preferentially ubiquitinated on endoplasmic reticulum luminal residues during HRD1 ubiquitin E3 ligase-mediated dislocation.

Burr ML, van den Boomen DJ, Bye H, Antrobus R, Wiertz EJ, Lehner PJ. Burr ML, et al. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14290-5. doi: 10.1073/pnas.1303380110. Epub 2013 Aug 8. Proc Natl Acad Sci U S A. 2013. PMID: 23929775 Free PMC article.

4

TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I.

van den Boomen DJ, Timms RT, Grice GL, Stagg HR, Skødt K, Dougan G, Nathan JA, Lehner PJ. van den Boomen DJ, et al. Proc Natl Acad Sci U S A. 2014 Aug 5;111(31):11425-30. doi: 10.1073/pnas.1409099111. Epub 2014 Jul 16. Proc Natl Acad Sci U S A. 2014. PMID: 25030448 Free PMC article.

5

Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141.

Hsu JL, van den Boomen DJ, Tomasec P, Weekes MP, Antrobus R, Stanton RJ, Ruckova E, Sugrue D, Wilkie GS, Davison AJ, Wilkinson GW, Lehner PJ. Hsu JL, et al. PLoS Pathog. 2015 Apr 14;11(4):e1004811. doi: 10.1371/journal.ppat.1004811. eCollection 2015 Apr. PLoS Pathog. 2015. PMID: 25875600 Free PMC article.

6

Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I.

van den Boomen DJ, Lehner PJ. van den Boomen DJ, et al. Mol Immunol. 2015 Dec;68(2 Pt A):106-11. doi: 10.1016/j.molimm.2015.07.005. Epub 2015 Jul 22. Mol Immunol. 2015. PMID: 26210183 Free PMC article. Review.

7

Temporal proteomic analysis of HIV infection reveals remodelling of the host phosphoproteome by lentiviral Vif variants.

Greenwood EJ, Matheson NJ, Wals K, van den Boomen DJ, Antrobus R, Williamson JC, Lehner PJ. Greenwood EJ, et al. Elife. 2016 Sep 30;5:e18296. doi: 10.7554/eLife.18296. Elife. 2016. PMID: 27690223 Free PMC article.

8

Multiple E2 ubiquitin-conjugating enzymes regulate human cytomegalovirus US2-mediated immunoreceptor downregulation.

van de Weijer ML, Schuren ABC, van den Boomen DJH, Mulder A, Claas FHJ, Lehner PJ, Lebbink RJ, Wiertz EJHJ. van de Weijer ML, et al. Among authors: van den boomen djh. J Cell Sci. 2017 Sep 1;130(17):2883-2892. doi: 10.1242/jcs.206839. Epub 2017 Jul 25. J Cell Sci. 2017. PMID: 28743740 Free PMC article.

9

MARCH6 and TRC8 facilitate the quality control of cytosolic and tail-anchored proteins.

Stefanovic-Barrett S, Dickson AS, Burr SP, Williamson JC, Lobb IT, van den Boomen DJ, Lehner PJ, Nathan JA. Stefanovic-Barrett S, et al. EMBO Rep. 2018 May;19(5):e45603. doi: 10.15252/embr.201745603. Epub 2018 Mar 8. EMBO Rep. 2018. PMID: 29519897 Free PMC article.

10

The sterol-responsive RNF145 E3 ubiquitin ligase mediates the degradation of HMG-CoA reductase together with gp78 and Hrd1.

Menzies SA, Volkmar N, van den Boomen DJ, Timms RT, Dickson AS, Nathan JA, Lehner PJ. Menzies SA, et al. Elife. 2018 Dec 13;7:e40009. doi: 10.7554/eLife.40009. Elife. 2018. PMID: 30543180 Free PMC article.

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