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De novo design of potent and resilient hACE2 decoys to neutralize SARS-CoV-2.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Barnes CO, Hsiang TY, Esser-Nobis K, Yu K, Reneer ZB, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric RS, Fuller DH, Walkey CD, Ross TM, Swanson R, Bjorkman PJ, Gale M Jr, Blancas-Mejia LM, Yen HL, Silva DA. Linsky TW, et al. Among authors: su w. Science. 2020 Dec 4;370(6521):1208-1214. doi: 10.1126/science.abe0075. Epub 2020 Nov 5. Science. 2020. PMID: 33154107 Free PMC article.
De novo design of ACE2 protein decoys to neutralize SARS-CoV-2.
Linsky TW, Vergara R, Codina N, Nelson JW, Walker MJ, Su W, Hsiang TY, Esser-Nobis K, Yu K, Hou YJ, Priya T, Mitsumoto M, Pong A, Lau UY, Mason ML, Chen J, Chen A, Berrocal T, Peng H, Clairmont NS, Castellanos J, Lin YR, Josephson-Day A, Baric R, Walkey CD, Swanson R, Gale M, Blancas-Mejia LM, Yen HL, Silva DA. Linsky TW, et al. Among authors: su w. bioRxiv [Preprint]. 2020 Aug 3:2020.08.03.231340. doi: 10.1101/2020.08.03.231340. bioRxiv. 2020. Update in: Science. 2020 Dec 4;370(6521):1208-1214. doi: 10.1126/science.abe0075 PMID: 32793910 Free PMC article. Updated. Preprint.
Neutralizing Monoclonal Antibodies That Target the Spike Receptor Binding Domain Confer Fc Receptor-Independent Protection against SARS-CoV-2 Infection in Syrian Hamsters.
Su W, Sia SF, Schmitz AJ, Bricker TL, Starr TN, Greaney AJ, Turner JS, Mohammed BM, Liu Z, Choy KT, Darling TL, Joshi A, Cheng KM, Wong AYL, Harastani HH, Nicholls JM, Whelan SPJ, Bloom JD, Yen HL, Ellebedy AH, Boon ACM. Su W, et al. mBio. 2021 Oct 26;12(5):e0239521. doi: 10.1128/mBio.02395-21. Epub 2021 Sep 14. mBio. 2021. PMID: 34517754 Free PMC article.
Ancestral sequence reconstruction pinpoints adaptations that enable avian influenza virus transmission in pigs.
Su W, Harfoot R, Su YCF, DeBeauchamp J, Joseph U, Jayakumar J, Crumpton JC, Jeevan T, Rubrum A, Franks J, Pascua PNQ, Kackos C, Zhang Y, Zhang M, Ji Y, Bui HT, Jones JC, Kercher L, Krauss S, Pleschka S, Chan MCW, Webster RG, Wu CY, Van Reeth K, Peiris M, Webby RJ, Smith GJD, Yen HL. Su W, et al. Among authors: su ycf. Nat Microbiol. 2021 Nov;6(11):1455-1465. doi: 10.1038/s41564-021-00976-y. Epub 2021 Oct 26. Nat Microbiol. 2021. PMID: 34702977 Free PMC article.
7,094 results