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Rational design of highly potent broad-spectrum enterovirus inhibitors targeting the nonstructural protein 2C.
Bauer L, Manganaro R, Zonsics B, Hurdiss DL, Zwaagstra M, Donselaar T, Welter NGE, van Kleef RGDM, Lopez ML, Bevilacqua F, Raman T, Ferla S, Bassetto M, Neyts J, Strating JRPM, Westerink RHS, Brancale A, van Kuppeveld FJM. Bauer L, et al. Among authors: bassetto m. PLoS Biol. 2020 Nov 6;18(11):e3000904. doi: 10.1371/journal.pbio.3000904. eCollection 2020 Nov. PLoS Biol. 2020. PMID: 33156822 Free PMC article.
Computer-aided identification, design and synthesis of a novel series of compounds with selective antiviral activity against chikungunya virus.
Bassetto M, De Burghgraeve T, Delang L, Massarotti A, Coluccia A, Zonta N, Gatti V, Colombano G, Sorba G, Silvestri R, Tron GC, Neyts J, Leyssen P, Brancale A. Bassetto M, et al. Antiviral Res. 2013 Apr;98(1):12-8. doi: 10.1016/j.antiviral.2013.01.002. Epub 2013 Feb 1. Antiviral Res. 2013. PMID: 23380636 Free article.
Design, synthesis and biological evaluation of 3,5-disubstituted 2-amino thiophene derivatives as a novel class of antitumor agents.
Romagnoli R, Baraldi PG, Lopez-Cara C, Salvador MK, Preti D, Tabrizi MA, Balzarini J, Nussbaumer P, Bassetto M, Brancale A, Fu XH, Yang-Gao, Li J, Zhang SZ, Hamel E, Bortolozzi R, Basso G, Viola G. Romagnoli R, et al. Among authors: bassetto m. Bioorg Med Chem. 2014 Sep 15;22(18):5097-109. doi: 10.1016/j.bmc.2013.12.030. Epub 2013 Dec 24. Bioorg Med Chem. 2014. PMID: 24398384 Free PMC article.
Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2)-receptor antagonists.
Wang X, Liu L, Huang L, Herbst-Robinson K, Cornec AS, James MJ, Sugiyama S, Bassetto M, Brancale A, Trojanowski JQ, Lee VM, Smith AB 3rd, Brunden KR, Ballatore C. Wang X, et al. Among authors: bassetto m. ACS Med Chem Lett. 2014 Jul 24;5(9):1015-20. doi: 10.1021/ml5002085. eCollection 2014 Sep 11. ACS Med Chem Lett. 2014. PMID: 25221659 Free PMC article.
Polyfluorinated groups in medicinal chemistry.
Bassetto M, Ferla S, Pertusati F. Bassetto M, et al. Future Med Chem. 2015;7(4):527-46. doi: 10.4155/fmc.15.5. Future Med Chem. 2015. PMID: 25875877 Review.
In silico structure-based design and synthesis of novel anti-RSV compounds.
Cancellieri M, Bassetto M, Widjaja I, van Kuppeveld F, de Haan CA, Brancale A. Cancellieri M, et al. Among authors: bassetto m. Antiviral Res. 2015 Oct;122:46-50. doi: 10.1016/j.antiviral.2015.08.003. Epub 2015 Aug 8. Antiviral Res. 2015. PMID: 26259810 Free article.
Structural biology in antiviral drug discovery.
Bassetto M, Massarotti A, Coluccia A, Brancale A. Bassetto M, et al. Curr Opin Pharmacol. 2016 Oct;30:116-130. doi: 10.1016/j.coph.2016.08.014. Epub 2016 Sep 6. Curr Opin Pharmacol. 2016. PMID: 27611878 Free PMC article. Review.
84 results