Liu CC - Search Results

1

Scalable continuous evolution for the generation of diverse enzyme variants encompassing promiscuous activities.

Rix G, Watkins-Dulaney EJ, Almhjell PJ, Boville CE, Arnold FH, Liu CC. Rix G, et al. Among authors: liu cc. Nat Commun. 2020 Nov 6;11(1):5644. doi: 10.1038/s41467-020-19539-6. Nat Commun. 2020. PMID: 33159067 Free PMC article.

2

Scalable, Continuous Evolution of Genes at Mutation Rates above Genomic Error Thresholds.

Ravikumar A, Arzumanyan GA, Obadi MKA, Javanpour AA, Liu CC. Ravikumar A, et al. Among authors: liu cc. Cell. 2018 Dec 13;175(7):1946-1957.e13. doi: 10.1016/j.cell.2018.10.021. Epub 2018 Nov 8. Cell. 2018. PMID: 30415839 Free PMC article.

3

Automated Continuous Evolution of Proteins in Vivo.

Zhong Z, Wong BG, Ravikumar A, Arzumanyan GA, Khalil AS, Liu CC. Zhong Z, et al. Among authors: liu cc. ACS Synth Biol. 2020 Jun 19;9(6):1270-1276. doi: 10.1021/acssynbio.0c00135. Epub 2020 May 12. ACS Synth Biol. 2020. PMID: 32374988 Free PMC article.

4

Systems for in vivo hypermutation: a quest for scale and depth in directed evolution.

Rix G, Liu CC. Rix G, et al. Among authors: liu cc. Curr Opin Chem Biol. 2021 Oct;64:20-26. doi: 10.1016/j.cbpa.2021.02.008. Epub 2021 Mar 27. Curr Opin Chem Biol. 2021. PMID: 33784581 Free PMC article. Review.

5

An in silico method to assess antibody fragment polyreactivity.

Harvey EP, Shin JE, Skiba MA, Nemeth GR, Hurley JD, Wellner A, Shaw AY, Miranda VG, Min JK, Liu CC, Marks DS, Kruse AC. Harvey EP, et al. Among authors: liu cc. Nat Commun. 2022 Dec 7;13(1):7554. doi: 10.1038/s41467-022-35276-4. Nat Commun. 2022. PMID: 36477674 Free PMC article.

6

In vivo hypermutation and continuous evolution.

Molina RS, Rix G, Mengiste AA, Alvarez B, Seo D, Chen H, Hurtado J, Zhang Q, Donato García-García J, Heins ZJ, Almhjell PJ, Arnold FH, Khalil AS, Hanson AD, Dueber JE, Schaffer DV, Chen F, Kim S, Ángel Fernández L, Shoulders MD, Liu CC. Molina RS, et al. Among authors: liu cc. Nat Rev Methods Primers. 2022;2:37. doi: 10.1038/s43586-022-00130-w. Epub 2022 May 19. Nat Rev Methods Primers. 2022. PMID: 37073402 Free PMC article. No abstract available.

7

Continuous evolution of user-defined genes at 1-million-times the genomic mutation rate.

Rix G, Williams RL, Spinner H, Hu VJ, Marks DS, Liu CC. Rix G, et al. Among authors: liu cc. bioRxiv [Preprint]. 2023 Nov 14:2023.11.13.566922. doi: 10.1101/2023.11.13.566922. bioRxiv. 2023. Update in: Science. 2024 Nov 8;386(6722):eadm9073. doi: 10.1126/science.adm9073 PMID: 38014077 Free PMC article. Updated. Preprint.

8

Directed evolution of aminoacyl-tRNA synthetases through in vivo hypermutation.

Furuhata Y, Rix G, Van Deventer JA, Liu CC. Furuhata Y, et al. Among authors: liu cc. bioRxiv [Preprint]. 2024 Sep 27:2024.09.27.615507. doi: 10.1101/2024.09.27.615507. bioRxiv. 2024. PMID: 39386665 Free PMC article. Preprint.

9

Continuous evolution of user-defined genes at 1 million times the genomic mutation rate.

Rix G, Williams RL, Hu VJ, Spinner A, Pisera AO, Marks DS, Liu CC. Rix G, et al. Among authors: liu cc. Science. 2024 Nov 8;386(6722):eadm9073. doi: 10.1126/science.adm9073. Epub 2024 Nov 8. Science. 2024. PMID: 39509492

10

An orthogonal DNA replication system in yeast.

Ravikumar A, Arrieta A, Liu CC. Ravikumar A, et al. Among authors: liu cc. Nat Chem Biol. 2014 Mar;10(3):175-7. doi: 10.1038/nchembio.1439. Epub 2014 Feb 2. Nat Chem Biol. 2014. PMID: 24487693

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