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6-methoxydihydroavicine, the alkaloid extracted from Macleaya cordata (Willd.) R. Br. (Papaveraceae), triggers RIPK1/Caspase-dependent cell death in pancreatic cancer cells through the disruption of oxaloacetic acid metabolism and accumulation of reactive oxygen species.
Ma N, Shangguan F, Zhou H, Huang H, Lei J, An J, Jin G, Zhuang W, Zhou S, Wu S, Xia H, Yang H, Lan L. Ma N, et al. Among authors: lan l. Phytomedicine. 2022 Jul 20;102:154164. doi: 10.1016/j.phymed.2022.154164. Epub 2022 May 13. Phytomedicine. 2022. PMID: 35597026
Hepatic SIRT6 deficit promotes liver tumorigenesis in the mice models.
Wang M, Lan L, Yang F, Jiang S, Xu H, Zhang C, Zhou G, Xia H, Xia J. Wang M, et al. Among authors: lan l. Genes Dis. 2020 Sep 2;9(3):789-796. doi: 10.1016/j.gendis.2020.08.007. eCollection 2022 May. Genes Dis. 2020. PMID: 35782983 Free PMC article.
2,030 results