Halsall JA - Search Results

1

Morphine leads to global genome changes in H3K27me3 levels via a Polycomb Repressive Complex 2 (PRC2) self-regulatory mechanism in mESCs.

Muñoa-Hoyos I, Halsall JA, Araolaza M, Ward C, Garcia I, Urizar-Arenaza I, Gianzo M, Garcia P, Turner B, Subirán N. Muñoa-Hoyos I, et al. Among authors: halsall ja. Clin Epigenetics. 2020 Nov 9;12(1):170. doi: 10.1186/s13148-020-00955-w. Clin Epigenetics. 2020. PMID: 33168052 Free PMC article.

2

Cells adapt to the epigenomic disruption caused by histone deacetylase inhibitors through a coordinated, chromatin-mediated transcriptional response.

Halsall JA, Turan N, Wiersma M, Turner BM. Halsall JA, et al. Epigenetics Chromatin. 2015 Sep 16;8:29. doi: 10.1186/s13072-015-0021-9. eCollection 2015. Epigenetics Chromatin. 2015. PMID: 26380582 Free PMC article.

3

Histone deacetylase inhibitors for cancer therapy: An evolutionarily ancient resistance response may explain their limited success.

Halsall JA, Turner BM. Halsall JA, et al. Bioessays. 2016 Nov;38(11):1102-1110. doi: 10.1002/bies.201600070. Epub 2016 Sep 22. Bioessays. 2016. PMID: 27717012 Free PMC article. Review.

4

Genes are often sheltered from the global histone hyperacetylation induced by HDAC inhibitors.

Halsall J, Gupta V, O'Neill LP, Turner BM, Nightingale KP. Halsall J, et al. PLoS One. 2012;7(3):e33453. doi: 10.1371/journal.pone.0033453. Epub 2012 Mar 30. PLoS One. 2012. PMID: 22479401 Free PMC article.

5

The histone deacetylase inhibitor sodium valproate causes limited transcriptional change in mouse embryonic stem cells but selectively overrides Polycomb-mediated Hoxb silencing.

Boudadi E, Stower H, Halsall JA, Rutledge CE, Leeb M, Wutz A, O'Neill LP, Nightingale KP, Turner BM. Boudadi E, et al. Among authors: halsall ja. Epigenetics Chromatin. 2013 May 1;6(1):11. doi: 10.1186/1756-8935-6-11. Epigenetics Chromatin. 2013. PMID: 23634885 Free PMC article.

6

Protein kinase Msk1 physically and functionally interacts with the KMT2A/MLL1 methyltransferase complex and contributes to the regulation of multiple target genes.

Wiersma M, Bussiere M, Halsall JA, Turan N, Slany R, Turner BM, Nightingale KP. Wiersma M, et al. Among authors: halsall ja. Epigenetics Chromatin. 2016 Nov 11;9:52. doi: 10.1186/s13072-016-0103-3. eCollection 2016. Epigenetics Chromatin. 2016. PMID: 27895715 Free PMC article.

7

Histone modifications form a cell-type-specific chromosomal bar code that persists through the cell cycle.

Halsall JA, Andrews S, Krueger F, Rutledge CE, Ficz G, Reik W, Turner BM. Halsall JA, et al. Sci Rep. 2021 Feb 4;11(1):3009. doi: 10.1038/s41598-021-82539-z. Sci Rep. 2021. PMID: 33542322 Free PMC article.

8

Immunostaining of modified histones defines high-level features of the human metaphase epigenome.

Terrenoire E, McRonald F, Halsall JA, Page P, Illingworth RS, Taylor AM, Davison V, O'Neill LP, Turner BM. Terrenoire E, et al. Among authors: halsall ja. Genome Biol. 2010;11(11):R110. doi: 10.1186/gb-2010-11-11-r110. Epub 2010 Nov 15. Genome Biol. 2010. PMID: 21078160 Free PMC article.

9

Immunolabelling of human metaphase chromosomes reveals the same banded distribution of histone H3 isoforms methylated at lysine 4 in primary lymphocytes and cultured cell lines.

Terrenoire E, Halsall JA, Turner BM. Terrenoire E, et al. Among authors: halsall ja. BMC Genet. 2015 Apr 29;16:44. doi: 10.1186/s12863-015-0200-5. BMC Genet. 2015. PMID: 25925961 Free PMC article.

10

A novel form of JARID2 is required for differentiation in lineage-committed cells.

Al-Raawi D, Jones R, Wijesinghe S, Halsall J, Petric M, Roberts S, Hotchin NA, Kanhere A. Al-Raawi D, et al. EMBO J. 2019 Feb 1;38(3):e98449. doi: 10.15252/embj.201798449. Epub 2018 Dec 20. EMBO J. 2019. PMID: 30573669 Free PMC article.

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