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The Group B Streptococcal surface antigen I/II protein, BspC, interacts with host vimentin to promote adherence to brain endothelium and inflammation during the pathogenesis of meningitis.
Deng L, Spencer BL, Holmes JA, Mu R, Rego S, Weston TA, Hu Y, Sanches GF, Yoon S, Park N, Nagao PE, Jenkinson HF, Thornton JA, Seo KS, Nobbs AH, Doran KS. Deng L, et al. PLoS Pathog. 2019 Jun 10;15(6):e1007848. doi: 10.1371/journal.ppat.1007848. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31181121 Free PMC article.
Cas9 Contributes to Group B Streptococcal Colonization and Disease.
Spencer BL, Deng L, Patras KA, Burcham ZM, Sanches GF, Nagao PE, Doran KS. Spencer BL, et al. Among authors: deng l. Front Microbiol. 2019 Aug 21;10:1930. doi: 10.3389/fmicb.2019.01930. eCollection 2019. Front Microbiol. 2019. PMID: 31497003 Free PMC article.
Bacterial protein domains with a novel Ig-like fold target human CEACAM receptors.
van Sorge NM, Bonsor DA, Deng L, Lindahl E, Schmitt V, Lyndin M, Schmidt A, Nilsson OR, Brizuela J, Boero E, Sundberg EJ, van Strijp JAG, Doran KS, Singer BB, Lindahl G, McCarthy AJ. van Sorge NM, et al. Among authors: deng l. EMBO J. 2021 Apr 1;40(7):e106103. doi: 10.15252/embj.2020106103. Epub 2021 Feb 1. EMBO J. 2021. PMID: 33522633 Free PMC article.
Bacteria hijack a meningeal neuroimmune axis to facilitate brain invasion.
Pinho-Ribeiro FA, Deng L, Neel DV, Erdogan O, Basu H, Yang D, Choi S, Walker AJ, Carneiro-Nascimento S, He K, Wu G, Stevens B, Doran KS, Levy D, Chiu IM. Pinho-Ribeiro FA, et al. Among authors: deng l. Nature. 2023 Mar;615(7952):472-481. doi: 10.1038/s41586-023-05753-x. Epub 2023 Mar 1. Nature. 2023. PMID: 36859544 Free PMC article.
S. aureus drives itch and scratch-induced skin damage through a V8 protease-PAR1 axis.
Deng L, Costa F, Blake KJ, Choi S, Chandrabalan A, Yousuf MS, Shiers S, Dubreuil D, Vega-Mendoza D, Rolland C, Deraison C, Voisin T, Bagood MD, Wesemann L, Frey AM, Palumbo JS, Wainger BJ, Gallo RL, Leyva-Castillo JM, Vergnolle N, Price TJ, Ramachandran R, Horswill AR, Chiu IM. Deng L, et al. Cell. 2023 Nov 22;186(24):5375-5393.e25. doi: 10.1016/j.cell.2023.10.019. Cell. 2023. PMID: 37995657 Free PMC article.
8,702 results