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Page 1
Brief Report: Dipyridamole Decreases Gut Mucosal Regulatory T-Cell Frequencies Among People With HIV on Antiretroviral Therapy.
Mallarino-Haeger C, Abebe KZ, Jackson EK, Zyhowski A, Klamar-Blain C, Cyktor JC, Comer D, Brand RM, Gillespie DG, Holleran K, Mellors JW, McGowan I, Riddler SA, Macatangay BJC. Mallarino-Haeger C, et al. Among authors: zyhowski a. J Acquir Immune Defic Syndr. 2020 Dec 15;85(5):665-669. doi: 10.1097/QAI.0000000000002488. J Acquir Immune Defic Syndr. 2020. PMID: 33177477 Free PMC article. Clinical Trial.
Tofacitinib inhibits inflammatory cytokines from ulcerative colitis and healthy mucosal explants and is associated with pSTAT1/3 reduction in T-cells.
Brand RM, Moore BA, Zyhowski A, Siegel A, Uttam S, Metter EJ, Engstrom J, Brand RE, Biswas N, Whitcomb DC, Binion DG, Schwartz M, McGowan I. Brand RM, et al. Among authors: zyhowski a. Am J Physiol Gastrointest Liver Physiol. 2021 Mar 1;320(3):G396-G410. doi: 10.1152/ajpgi.00383.2020. Epub 2020 Dec 23. Am J Physiol Gastrointest Liver Physiol. 2021. PMID: 33355506 Free PMC article.
Phase I Dose Volume Escalation of Rectally Administered PC-1005 to Assess Safety, Pharmacokinetics, and Antiviral Pharmacodynamics as a Multipurpose Prevention Technology (MTN-037).
Ho K, Hoesley C, Anderson PL, Fernández-Romero JA, Friedland BA, Kelly CW, Jiao Y, Edick S, Brand R, Kunjara Na Ayudhya RP, Zyhowski A, Hartman DJ, Reddy NB, Al-Khouja A, Piper J, Bauermeister JA, Teleshova N, Melo C, Cornejal N, Barnable P, Singh D, Scheckter R, McClure T, Hillier SL, Hendrix CW; MTN-037 Study Team. Ho K, et al. Among authors: zyhowski a. J Acquir Immune Defic Syndr. 2024 Dec 1;97(4):379-386. doi: 10.1097/QAI.0000000000003506. J Acquir Immune Defic Syndr. 2024. PMID: 39808074 Clinical Trial.
Tenofovir, emtricitabine, lamivudine and dolutegravir concentrations in plasma and urine following drug intake cessation in a randomized controlled directly observed pharmacokinetic trial to aid point-of-care testing.
Else LJ, Dickinson L, Edick S, Zyhowski A, Ho K, Meyn L, Dilly-Penchala S, Thompson B, Shaw V, Khoo S, Brand RM. Else LJ, et al. Among authors: zyhowski a. J Antimicrob Chemother. 2024 Jul 1;79(7):1597-1605. doi: 10.1093/jac/dkae147. J Antimicrob Chemother. 2024. PMID: 38758205 Free PMC article. Clinical Trial.
Immune microenvironment profiling of normal appearing colorectal mucosa biopsied over repeat patient visits reproducibly separates lynch syndrome patients based on their history of colon cancer.
Brand RM, Dudley B, Karloski E, Zyhowski A, Raphael R, Pitlor D, Metter EJ, Pai R, Lee K, Brand RE, Uttam S. Brand RM, et al. Among authors: zyhowski a. Front Oncol. 2023 Aug 11;13:1174831. doi: 10.3389/fonc.2023.1174831. eCollection 2023. Front Oncol. 2023. PMID: 37637062 Free PMC article.
Immune Microenvironment Profiling of Normal Appearing Colorectal Mucosa Biopsied Over Repeat Patient Visits Reproduciably Separates Lynch Syndrome Patients Based on Their History of Colon Cancer.
Brand RM, Dudley B, Karloski E, Zyhowski A, Raphael R, Pitlor D, Metter EJ, Pai R, Lee K, Brand RE, Uttam S. Brand RM, et al. Among authors: zyhowski a. medRxiv [Preprint]. 2023 Mar 6:2023.03.03.23286594. doi: 10.1101/2023.03.03.23286594. medRxiv. 2023. Update in: Front Oncol. 2023 Aug 11;13:1174831. doi: 10.3389/fonc.2023.1174831 PMID: 36945451 Free PMC article. Updated. Preprint.