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Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.
Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA. Kim HS, et al. Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24. Cell. 2013. PMID: 24243015 Free PMC article.
Selective targeting of mutant adenomatous polyposis coli (APC) in colorectal cancer.
Zhang L, Theodoropoulos PC, Eskiocak U, Wang W, Moon YA, Posner B, Williams NS, Wright WE, Kim SB, Nijhawan D, De Brabander JK, Shay JW. Zhang L, et al. Among authors: de brabander jk. Sci Transl Med. 2016 Oct 19;8(361):361ra140. doi: 10.1126/scitranslmed.aaf8127. Sci Transl Med. 2016. PMID: 27798265 Free PMC article.
Identification of Trypanosoma brucei AdoMetDC Inhibitors Using a High-Throughput Mass Spectrometry-Based Assay.
Volkov OA, Cosner CC, Brockway AJ, Kramer M, Booker M, Zhong S, Ketcherside A, Wei S, Longgood J, McCoy M, Richardson TE, Wring SA, Peel M, Klinger JD, Posner BA, De Brabander JK, Phillips MA. Volkov OA, et al. Among authors: de brabander jk. ACS Infect Dis. 2017 Jul 14;3(7):512-526. doi: 10.1021/acsinfecdis.7b00022. Epub 2017 Apr 7. ACS Infect Dis. 2017. PMID: 28350440 Free PMC article.
Molecular mechanism of the wake-promoting agent TAK-925.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Among authors: de brabander jk. Nat Commun. 2022 May 25;13(1):2902. doi: 10.1038/s41467-022-30601-3. Nat Commun. 2022. PMID: 35614071 Free PMC article.
TK216 targets microtubules in Ewing sarcoma cells.
Povedano JM, Li V, Lake KE, Bai X, Rallabandi R, Kim J, Xie Y, De Brabander JK, McFadden DG. Povedano JM, et al. Among authors: de brabander jk. Cell Chem Biol. 2022 Aug 18;29(8):1325-1332.e4. doi: 10.1016/j.chembiol.2022.06.002. Epub 2022 Jul 7. Cell Chem Biol. 2022. PMID: 35803262 Free PMC article.
79 results