Ye X - Search Results

1

A Multipronged Approach Establishes Covalent Modification of β-Tubulin as the Mode of Action of Benzamide Anti-cancer Toxins.

Povedano JM, Rallabandi R, Bai X, Ye X, Liou J, Chen H, Kim J, Xie Y, Posner B, Rice L, De Brabander JK, McFadden DG. Povedano JM, et al. Among authors: ye x. J Med Chem. 2020 Nov 25;63(22):14054-14066. doi: 10.1021/acs.jmedchem.0c01482. Epub 2020 Nov 12. J Med Chem. 2020. PMID: 33180487 Free PMC article.

2

A TOG:αβ-tubulin complex structure reveals conformation-based mechanisms for a microtubule polymerase.

Ayaz P, Ye X, Huddleston P, Brautigam CA, Rice LM. Ayaz P, et al. Among authors: ye x. Science. 2012 Aug 17;337(6096):857-60. doi: 10.1126/science.1221698. Science. 2012. PMID: 22904013 Free PMC article.

3

A mutation uncouples the tubulin conformational and GTPase cycles, revealing allosteric control of microtubule dynamics.

Geyer EA, Burns A, Lalonde BA, Ye X, Piedra FA, Huffaker TC, Rice LM. Geyer EA, et al. Among authors: ye x. Elife. 2015 Oct 6;4:e10113. doi: 10.7554/eLife.10113. Elife. 2015. PMID: 26439009 Free PMC article.

4

GDP-to-GTP exchange on the microtubule end can contribute to the frequency of catastrophe.

Piedra FA, Kim T, Garza ES, Geyer EA, Burns A, Ye X, Rice LM. Piedra FA, et al. Among authors: ye x. Mol Biol Cell. 2016 Nov 7;27(22):3515-3525. doi: 10.1091/mbc.E16-03-0199. Epub 2016 May 4. Mol Biol Cell. 2016. PMID: 27146111 Free PMC article.

5

Insights into allosteric control of microtubule dynamics from a buried β-tubulin mutation that causes faster growth and slower shrinkage.

Ye X, Kim T, Geyer EA, Rice LM. Ye X, et al. Protein Sci. 2020 Jun;29(6):1429-1439. doi: 10.1002/pro.3842. Epub 2020 Mar 9. Protein Sci. 2020. PMID: 32077153 Free PMC article.

6

Cryo-EM structure of VASH1-SVBP bound to microtubules.

Li F, Li Y, Ye X, Gao H, Shi Z, Luo X, Rice LM, Yu H. Li F, et al. Among authors: ye x. Elife. 2020 Aug 10;9:e58157. doi: 10.7554/eLife.58157. Elife. 2020. PMID: 32773040 Free PMC article.

7

Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral response.

Seo D, Brito Oliveira S, Rex EA, Ye X, Rice LM, da Fonseca FG, Gammon DB. Seo D, et al. Among authors: ye x. Cell Rep. 2024 Mar 26;43(3):113882. doi: 10.1016/j.celrep.2024.113882. Epub 2024 Mar 7. Cell Rep. 2024. PMID: 38457341 Free PMC article.

8

Functional anatomy of the Drosophila microRNA-generating enzyme.

Ye X, Paroo Z, Liu Q. Ye X, et al. J Biol Chem. 2007 Sep 28;282(39):28373-28378. doi: 10.1074/jbc.M705208200. Epub 2007 Jul 31. J Biol Chem. 2007. PMID: 17666393 Free article.

9

Structure of C3PO and mechanism of human RISC activation.

Ye X, Huang N, Liu Y, Paroo Z, Huerta C, Li P, Chen S, Liu Q, Zhang H. Ye X, et al. Nat Struct Mol Biol. 2011 Jun;18(6):650-7. doi: 10.1038/nsmb.2032. Epub 2011 May 8. Nat Struct Mol Biol. 2011. PMID: 21552258 Free PMC article.

10

C3PO, an endoribonuclease that promotes RNAi by facilitating RISC activation.

Liu Y, Ye X, Jiang F, Liang C, Chen D, Peng J, Kinch LN, Grishin NV, Liu Q. Liu Y, et al. Among authors: ye x. Science. 2009 Aug 7;325(5941):750-3. doi: 10.1126/science.1176325. Science. 2009. PMID: 19661431 Free PMC article.

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