Schaaf TM - Search Results

1

Fluorescence-Based TNFR1 Biosensor for Monitoring Receptor Structural and Conformational Dynamics and Discovery of Small Molecule Modulators.

Lo CH, Schaaf TM, Thomas DD, Sachs JN. Lo CH, et al. Among authors: schaaf tm. Methods Mol Biol. 2021;2248:121-137. doi: 10.1007/978-1-0716-1130-2_9. Methods Mol Biol. 2021. PMID: 33185872

2

Discovery of enzyme modulators via high-throughput time-resolved FRET in living cells.

Gruber SJ, Cornea RL, Li J, Peterson KC, Schaaf TM, Gillispie GD, Dahl R, Zsebo KM, Robia SL, Thomas DD. Gruber SJ, et al. Among authors: schaaf tm. J Biomol Screen. 2014 Feb;19(2):215-22. doi: 10.1177/1087057113510740. J Biomol Screen. 2014. PMID: 24436077 Free PMC article.

3

High-Throughput Spectral and Lifetime-Based FRET Screening in Living Cells to Identify Small-Molecule Effectors of SERCA.

Schaaf TM, Peterson KC, Grant BD, Bawaskar P, Yuen S, Li J, Muretta JM, Gillispie GD, Thomas DD. Schaaf TM, et al. SLAS Discov. 2017 Mar;22(3):262-273. doi: 10.1177/1087057116680151. Epub 2016 Dec 13. SLAS Discov. 2017. PMID: 27899691 Free PMC article.

4

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors.

Lo CH, Vunnam N, Lewis AK, Chiu TL, Brummel BE, Schaaf TM, Grant BD, Bawaskar P, Thomas DD, Sachs JN. Lo CH, et al. Among authors: schaaf tm. SLAS Discov. 2017 Sep;22(8):950-961. doi: 10.1177/2472555217706478. Epub 2017 May 22. SLAS Discov. 2017. PMID: 28530838 Free PMC article.

5

Noncompetitive inhibitors of TNFR1 probe conformational activation states.

Lo CH, Schaaf TM, Grant BD, Lim CK, Bawaskar P, Aldrich CC, Thomas DD, Sachs JN. Lo CH, et al. Among authors: schaaf tm. Sci Signal. 2019 Jul 30;12(592):eaav5637. doi: 10.1126/scisignal.aav5637. Sci Signal. 2019. PMID: 31363069 Free PMC article.

6

Spectral Unmixing Plate Reader: High-Throughput, High-Precision FRET Assays in Living Cells.

Schaaf TM, Peterson KC, Grant BD, Thomas DD, Gillispie GD. Schaaf TM, et al. SLAS Discov. 2017 Mar;22(3):250-261. doi: 10.1177/1087057116679637. Epub 2016 Nov 23. SLAS Discov. 2017. PMID: 27879398 Free PMC article.

7

Targeting protein-protein interactions for therapeutic discovery via FRET-based high-throughput screening in living cells.

Stroik DR, Yuen SL, Janicek KA, Schaaf TM, Li J, Ceholski DK, Hajjar RJ, Cornea RL, Thomas DD. Stroik DR, et al. Among authors: schaaf tm. Sci Rep. 2018 Aug 22;8(1):12560. doi: 10.1038/s41598-018-29685-z. Sci Rep. 2018. PMID: 30135432 Free PMC article.

8

Red-Shifted FRET Biosensors for High-Throughput Fluorescence Lifetime Screening.

Schaaf TM, Li A, Grant BD, Peterson K, Yuen S, Bawaskar P, Kleinboehl E, Li J, Thomas DD, Gillispie GD. Schaaf TM, et al. Biosensors (Basel). 2018 Oct 24;8(4):99. doi: 10.3390/bios8040099. Biosensors (Basel). 2018. PMID: 30352972 Free PMC article.

9

Live-Cell Cardiac-Specific High-Throughput Screening Platform for Drug-Like Molecules that Enhance Ca²⁺ Transport.

Schaaf TM, Kleinboehl E, Yuen SL, Roelike LN, Svensson B, Thompson AR, Cornea RL, Thomas DD. Schaaf TM, et al. Cells. 2020 May 8;9(5):1170. doi: 10.3390/cells9051170. Cells. 2020. PMID: 32397211 Free PMC article.

10

Consequences of inequity in the neurosurgical workforce: Lessons from traumatic brain injury.

Venkatesh S, Bravo M, Schaaf T, Koller M, Sundeen K, Samadani U. Venkatesh S, et al. Front Surg. 2022 Sep 1;9:962867. doi: 10.3389/fsurg.2022.962867. eCollection 2022. Front Surg. 2022. PMID: 36117842 Free PMC article. Review.

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