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Page 1
The PI3K pathway preserves metabolic health through MARCO-dependent lipid uptake by adipose tissue macrophages.
Brunner JS, Vogel A, Lercher A, Caldera M, Korosec A, Pühringer M, Hofmann M, Hajto A, Kieler M, Garrido LQ, Kerndl M, Kuttke M, Mesteri I, Górna MW, Kulik M, Dominiak PM, Brandon AE, Estevez E, Egan CL, Gruber F, Schweiger M, Menche J, Bergthaler A, Weichhart T, Klavins K, Febbraio MA, Sharif O, Schabbauer G. Brunner JS, et al. Nat Metab. 2020 Dec;2(12):1427-1442. doi: 10.1038/s42255-020-00311-5. Epub 2020 Nov 16. Nat Metab. 2020. PMID: 33199895
Loss of phosphatase and tensin homolog (PTEN) in myeloid cells controls inflammatory bone destruction by regulating the osteoclastogenic potential of myeloid cells.
Blüml S, Friedrich M, Lohmeyer T, Sahin E, Saferding V, Brunner J, Puchner A, Mandl P, Niederreiter B, Smolen JS, Schabbauer G, Redlich K. Blüml S, et al. Among authors: brunner j. Ann Rheum Dis. 2015 Jan;74(1):227-33. doi: 10.1136/annrheumdis-2013-203486. Epub 2013 Sep 27. Ann Rheum Dis. 2015. PMID: 24078675
The triggering receptor expressed on myeloid cells 2 inhibits complement component 1q effector mechanisms and exerts detrimental effects during pneumococcal pneumonia.
Sharif O, Gawish R, Warszawska JM, Martins R, Lakovits K, Hladik A, Doninger B, Brunner J, Korosec A, Schwarzenbacher RE, Berg T, Kralovics R, Colinge J, Mesteri I, Gilfillan S, Salmaggi A, Verschoor A, Colonna M, Knapp S. Sharif O, et al. PLoS Pathog. 2014 Jun 12;10(6):e1004167. doi: 10.1371/journal.ppat.1004167. eCollection 2014 Jun. PLoS Pathog. 2014. PMID: 24945405 Free PMC article.
Macrophage PTEN regulates expression and secretion of arginase I modulating innate and adaptive immune responses.
Sahin E, Haubenwallner S, Kuttke M, Kollmann I, Halfmann A, Dohnal AM, Chen L, Cheng P, Hoesel B, Einwallner E, Brunner J, Kral JB, Schrottmaier WC, Thell K, Saferding V, Blüml S, Schabbauer G. Sahin E, et al. J Immunol. 2014 Aug 15;193(4):1717-27. doi: 10.4049/jimmunol.1302167. Epub 2014 Jul 11. J Immunol. 2014. PMID: 25015834 Free PMC article.
Loss of Phosphatase and Tensin Homolog in APCs Impedes Th17-Mediated Autoimmune Encephalomyelitis.
Sahin E, Brunner JS, Kral JB, Kuttke M, Hanzl L, Datler H, Paar H, Neuwinger N, Saferding V, Zinser E, Halfmann A, Soukup K, Hainzl E, Lohmeyer T, Niederreiter B, Haider T, Dohnal AM, Krönke G, Blüml S, Schabbauer G. Sahin E, et al. Among authors: brunner js. J Immunol. 2015 Sep 15;195(6):2560-70. doi: 10.4049/jimmunol.1402511. Epub 2015 Aug 5. J Immunol. 2015. PMID: 26246144
Phosphatase and tensin homolog (PTEN) in antigen-presenting cells controls Th17-mediated autoimmune arthritis.
Blüml S, Sahin E, Saferding V, Goncalves-Alves E, Hainzl E, Niederreiter B, Hladik A, Lohmeyer T, Brunner JS, Bonelli M, Koenders MI, van den Berg WB, Superti-Furga G, Smolen JS, Schabbauer G, Redlich K. Blüml S, et al. Among authors: brunner js. Arthritis Res Ther. 2015 Aug 26;17(1):230. doi: 10.1186/s13075-015-0742-y. Arthritis Res Ther. 2015. PMID: 26307404 Free PMC article.
Myeloid PTEN deficiency impairs tumor-immune surveillance via immune-checkpoint inhibition.
Kuttke M, Sahin E, Pisoni J, Percig S, Vogel A, Kraemmer D, Hanzl L, Brunner JS, Paar H, Soukup K, Halfmann A, Dohnal AM, Steiner CW, Blüml S, Basilio J, Hochreiter B, Salzmann M, Hoesel B, Lametschwandtner G, Eferl R, Schmid JA, Schabbauer G. Kuttke M, et al. Among authors: brunner js. Oncoimmunology. 2016 Mar 28;5(7):e1164918. doi: 10.1080/2162402X.2016.1164918. eCollection 2016 Jul. Oncoimmunology. 2016. PMID: 27622019 Free PMC article.
MicroRNA-146a governs fibroblast activation and joint pathology in arthritis.
Saferding V, Puchner A, Goncalves-Alves E, Hofmann M, Bonelli M, Brunner JS, Sahin E, Niederreiter B, Hayer S, Kiener HP, Einwallner E, Nehmar R, Carapito R, Georgel P, Koenders MI, Boldin M, Schabbauer G, Kurowska-Stolarska M, Steiner G, Smolen JS, Redlich K, Blüml S. Saferding V, et al. Among authors: brunner js. J Autoimmun. 2017 Aug;82:74-84. doi: 10.1016/j.jaut.2017.05.006. Epub 2017 May 22. J Autoimmun. 2017. PMID: 28545737 Free PMC article.
39 results