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Modulating the tumor microenvironment via oncolytic virus and PI3K inhibition synergistically restores immune checkpoint therapy response in PTEN-deficient glioblastoma.
Xing F, Xiao J, Wu J, Liang J, Lu X, Guo L, Li P, Hou P, Li C, Guo D. Xing F, et al. Among authors: guo d, guo l. Signal Transduct Target Ther. 2021 Jul 28;6(1):275. doi: 10.1038/s41392-021-00609-0. Signal Transduct Target Ther. 2021. PMID: 34315854 Free PMC article. No abstract available.
The RNA polymerase of cytoplasmically replicating Zika virus binds with chromatin DNA in nuclei and regulates host gene transcription.
Li P, Wu J, Liu S, Lu R, Jiang H, Wang N, Luo M, Guo L, Xiao J, Bu L, Liu L, Xing F, Peng H, Li C, Ma L, Zhao B, Zhou Z, Guo D. Li P, et al. Among authors: guo d, guo l. Proc Natl Acad Sci U S A. 2022 Dec 6;119(49):e2205013119. doi: 10.1073/pnas.2205013119. Epub 2022 Nov 29. Proc Natl Acad Sci U S A. 2022. PMID: 36442102 Free PMC article.
SARS-CoV-2 ORF3a sensitizes cells to ferroptosis via Keap1-NRF2 axis.
Liu L, Du J, Yang S, Zheng B, Shen J, Huang J, Cao L, Huang S, Liu X, Guo L, Li C, Ke C, Peng X, Guo D, Peng H. Liu L, et al. Among authors: guo d, guo l. Redox Biol. 2023 Jul;63:102752. doi: 10.1016/j.redox.2023.102752. Epub 2023 May 23. Redox Biol. 2023. PMID: 37245288 Free PMC article.
Substrate stiffness dictates unique doxorubicin-induced senescence-associated secretory phenotypes and transcriptomic signatures in human pulmonary fibroblasts.
Du H, Rose JP, Bons J, Guo L, Valentino TR, Wu F, Burton JB, Basisty N, Manwaring-Mueller M, Makhijani P, Chen N, Chang V, Winer S, Campisi J, Furman D, Nagy A, Schilling B, Winer DA. Du H, et al. Among authors: guo l. Geroscience. 2025 Jan 18. doi: 10.1007/s11357-025-01507-x. Online ahead of print. Geroscience. 2025. PMID: 39826027
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