Ko CJ - Search Results

1

The E3 ubiquitin ligase Peli1 regulates the metabolic actions of mTORC1 to suppress antitumor T cell responses.

Ko CJ, Zhang L, Jie Z, Zhu L, Zhou X, Xie X, Gao T, Yang JY, Cheng X, Sun SC. Ko CJ, et al. EMBO J. 2021 Jan 15;40(2):e104532. doi: 10.15252/embj.2020104532. Epub 2020 Nov 20. EMBO J. 2021. PMID: 33215753 Free PMC article.

2

TBKBP1 and TBK1 form a growth factor signalling axis mediating immunosuppression and tumourigenesis.

Zhu L, Li Y, Xie X, Zhou X, Gu M, Jie Z, Ko CJ, Gao T, Hernandez BE, Cheng X, Sun SC. Zhu L, et al. Among authors: ko cj. Nat Cell Biol. 2019 Dec;21(12):1604-1614. doi: 10.1038/s41556-019-0429-8. Epub 2019 Dec 2. Nat Cell Biol. 2019. PMID: 31792381 Free PMC article.

3

Intestinal Epithelial TBK1 Prevents Differentiation of T-helper 17 Cells and Tumorigenesis in Mice.

Yang JY, Jie Z, Mathews A, Zhou X, Li Y, Gu M, Xie X, Ko CJ, Cheng X, Qi Y, Estrella JS, Wang J, Sun SC. Yang JY, et al. Among authors: ko cj. Gastroenterology. 2020 Nov;159(5):1793-1806. doi: 10.1053/j.gastro.2020.07.047. Epub 2020 Jul 31. Gastroenterology. 2020. PMID: 32745468 Free PMC article.

4

TRAF2 regulates T cell immunity by maintaining a Tpl2-ERK survival signaling axis in effector and memory CD8 T cells.

Xie X, Zhu L, Jie Z, Li Y, Gu M, Zhou X, Wang H, Chang JH, Ko CJ, Cheng X, Sun SC. Xie X, et al. Among authors: ko cj. Cell Mol Immunol. 2021 Sep;18(9):2262-2274. doi: 10.1038/s41423-020-00583-7. Epub 2020 Nov 17. Cell Mol Immunol. 2021. PMID: 33203937 Free PMC article.

5

DYRK1a mediates BAFF-induced noncanonical NF-κB activation to promote autoimmunity and B-cell leukemogenesis.

Li Y, Xie X, Jie Z, Zhu L, Yang JY, Ko CJ, Gao T, Jain A, Jung SY, Baran N, Konopleva MY, Cheng X, Sun SC. Li Y, et al. Among authors: ko cj. Blood. 2021 Dec 9;138(23):2360-2371. doi: 10.1182/blood.2021011247. Blood. 2021. PMID: 34255829 Free PMC article.

6

Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway.

Jie Z, Ko CJ, Wang H, Xie X, Li Y, Gu M, Zhu L, Yang JY, Gao T, Ru W, Tang SJ, Cheng X, Sun SC. Jie Z, et al. Among authors: ko cj. Sci Adv. 2021 Sep 3;7(36):eabh0609. doi: 10.1126/sciadv.abh0609. Epub 2021 Sep 3. Sci Adv. 2021. PMID: 34516909 Free PMC article.

7

Peli1 facilitates NLRP3 inflammasome activation by mediating ASC ubiquitination.

Zhang L, Ko CJ, Li Y, Jie Z, Zhu L, Zhou X, Xie X, Gao T, Liu T, Cheng X, Sun SC. Zhang L, et al. Among authors: ko cj. Cell Rep. 2021 Oct 26;37(4):109904. doi: 10.1016/j.celrep.2021.109904. Cell Rep. 2021. PMID: 34706239 Free article.

8

Myeloid cell TBK1 restricts inflammatory responses.

Gao T, Liu T, Ko CJ, Zhang L, Joo D, Xie X, Zhu L, Li Y, Cheng X, Sun SC. Gao T, et al. Among authors: ko cj. Proc Natl Acad Sci U S A. 2022 Jan 25;119(4):e2107742119. doi: 10.1073/pnas.2107742119. Proc Natl Acad Sci U S A. 2022. PMID: 35074921 Free PMC article.

9

Dapl1 controls NFATc2 activation to regulate CD8⁺ T cell exhaustion and responses in chronic infection and cancer.

Zhu L, Zhou X, Gu M, Kim J, Li Y, Ko CJ, Xie X, Gao T, Cheng X, Sun SC. Zhu L, et al. Among authors: ko cj. Nat Cell Biol. 2022 Jul;24(7):1165-1176. doi: 10.1038/s41556-022-00942-8. Epub 2022 Jun 30. Nat Cell Biol. 2022. PMID: 35773432 Free PMC article.

10

TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responses.

Li Y, Zhu L, Ko CJ, Yang JY, Wang H, Manyam G, Wang J, Cheng X, Zhao S, Jie Z. Li Y, et al. Among authors: ko cj. J Exp Med. 2023 Aug 7;220(8):e20221483. doi: 10.1084/jem.20221483. Epub 2023 Apr 25. J Exp Med. 2023. PMID: 37097293 Free PMC article.

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