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Page 1
ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B.
Zyryanova AF, Kashiwagi K, Rato C, Harding HP, Crespillo-Casado A, Perera LA, Sakamoto A, Nishimoto M, Yonemochi M, Shirouzu M, Ito T, Ron D. Zyryanova AF, et al. Among authors: yonemochi m. Mol Cell. 2021 Jan 7;81(1):88-103.e6. doi: 10.1016/j.molcel.2020.10.031. Epub 2020 Nov 20. Mol Cell. 2021. PMID: 33220178 Free PMC article.
Structural basis for eIF2B inhibition in integrated stress response.
Kashiwagi K, Yokoyama T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Shirouzu M, Ito T. Kashiwagi K, et al. Among authors: yonemochi m. Science. 2019 May 3;364(6439):495-499. doi: 10.1126/science.aaw4104. Science. 2019. PMID: 31048492
HCV IRES Captures an Actively Translating 80S Ribosome.
Yokoyama T, Machida K, Iwasaki W, Shigeta T, Nishimoto M, Takahashi M, Sakamoto A, Yonemochi M, Harada Y, Shigematsu H, Shirouzu M, Tadakuma H, Imataka H, Ito T. Yokoyama T, et al. Among authors: yonemochi m. Mol Cell. 2019 Jun 20;74(6):1205-1214.e8. doi: 10.1016/j.molcel.2019.04.022. Epub 2019 May 9. Mol Cell. 2019. PMID: 31080011 Free article.
Cryo-EM structure of the human ELMO1-DOCK5-Rac1 complex.
Kukimoto-Niino M, Katsura K, Kaushik R, Ehara H, Yokoyama T, Uchikubo-Kamo T, Nakagawa R, Mishima-Tsumagari C, Yonemochi M, Ikeda M, Hanada K, Zhang KYJ, Shirouzu M. Kukimoto-Niino M, et al. Among authors: yonemochi m. Sci Adv. 2021 Jul 21;7(30):eabg3147. doi: 10.1126/sciadv.abg3147. Print 2021 Jul. Sci Adv. 2021. PMID: 34290093 Free PMC article.
Targeting Ras-binding domain of ELMO1 by computational nanobody design.
Tam C, Kukimoto-Niino M, Miyata-Yabuki Y, Tsuda K, Mishima-Tsumagari C, Ihara K, Inoue M, Yonemochi M, Hanada K, Matsumoto T, Shirouzu M, Zhang KYJ. Tam C, et al. Among authors: yonemochi m. Commun Biol. 2023 Mar 17;6(1):284. doi: 10.1038/s42003-023-04657-w. Commun Biol. 2023. PMID: 36932164 Free PMC article.