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Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2.
Guragossian N, Belhani B, Moreno A, Nunes MT, Gonzalez-Lobato L, Marminon C, Berthier L, Rocio Andrade Pires AD, Özvegy-Laczka C, Sarkadi B, Terreux R, Bouaziz Z, Berredjem M, Jose J, Di Pietro A, Falson P, Le Borgne M. Guragossian N, et al. Among authors: terreux r. Eur J Med Chem. 2021 Feb 5;211:113017. doi: 10.1016/j.ejmech.2020.113017. Epub 2020 Nov 12. Eur J Med Chem. 2021. PMID: 33223263
Investigation of chalcones as selective inhibitors of the breast cancer resistance protein: critical role of methoxylation in both inhibition potency and cytotoxicity.
Valdameri G, Gauthier C, Terreux R, Kachadourian R, Day BJ, Winnischofer SM, Rocha ME, Frachet V, Ronot X, Di Pietro A, Boumendjel A. Valdameri G, et al. Among authors: terreux r. J Med Chem. 2012 Apr 12;55(7):3193-200. doi: 10.1021/jm2016528. Epub 2012 Apr 2. J Med Chem. 2012. PMID: 22449016 Free PMC article.
55 results