Leskov K - Search Results

1

Single-cell lineage analysis reveals extensive multimodal transcriptional control during directed beta-cell differentiation.

Weng C, Xi J, Li H, Cui J, Gu A, Lai S, Leskov K, Ke L, Jin F, Li Y. Weng C, et al. Among authors: leskov k. Nat Metab. 2020 Dec;2(12):1443-1458. doi: 10.1038/s42255-020-00314-2. Epub 2020 Nov 30. Nat Metab. 2020. PMID: 33257854 Free PMC article.

2

Single cell multiomic analysis reveals diabetes-associated β-cell heterogeneity driven by HNF1A.

Weng C, Gu A, Zhang S, Lu L, Ke L, Gao P, Liu X, Wang Y, Hu P, Plummer D, MacDonald E, Zhang S, Xi J, Lai S, Leskov K, Yuan K, Jin F, Li Y. Weng C, et al. Among authors: leskov k. Nat Commun. 2023 Sep 5;14(1):5400. doi: 10.1038/s41467-023-41228-3. Nat Commun. 2023. PMID: 37669939 Free PMC article.

3

Biogenesis of P-TEFb in CD4+ T cells to reverse HIV latency is mediated by protein kinase C (PKC)-independent signaling pathways.

Mbonye U, Leskov K, Shukla M, Valadkhan S, Karn J. Mbonye U, et al. Among authors: leskov k. PLoS Pathog. 2021 Sep 16;17(9):e1009581. doi: 10.1371/journal.ppat.1009581. eCollection 2021 Sep. PLoS Pathog. 2021. PMID: 34529720 Free PMC article.

4

Human neuroblastoma cells rapidly enter cell cycle arrest and apoptosis following exposure to C-28 derivatives of the synthetic triterpenoid CDDO.

Alabran JL, Cheuk A, Liby K, Sporn M, Khan J, Letterio J, Leskov KS. Alabran JL, et al. Among authors: leskov ks. Cancer Biol Ther. 2008 May;7(5):709-17. doi: 10.4161/cbt.7.5.5713. Epub 2008 May 7. Cancer Biol Ther. 2008. PMID: 18277094 Free PMC article.

5

Structural rearrangements in the nucleus localize latent HIV proviruses to a perinucleolar compartment supportive of reactivation.

Kizito F, Nguyen K, Mbonye U, Shukla M, Luttge B, Checkley MA, Agaponova A, Leskov K, Karn J. Kizito F, et al. Among authors: leskov k. Proc Natl Acad Sci U S A. 2024 Apr 30;121(18):e2202003121. doi: 10.1073/pnas.2202003121. Epub 2024 Apr 26. Proc Natl Acad Sci U S A. 2024. PMID: 38669184 Free PMC article.

6

IR-inducible clusterin gene expression: a protein with potential roles in ionizing radiation-induced adaptive responses, genomic instability, and bystander effects.

Klokov D, Criswell T, Leskov KS, Araki S, Mayo L, Boothman DA. Klokov D, et al. Mutat Res. 2004 Dec 2;568(1):97-110. doi: 10.1016/j.mrfmmm.2004.06.049. Mutat Res. 2004. PMID: 15530543 Review.

7

Bax-inhibiting peptides derived from Ku70 and cell-penetrating pentapeptides.

Gomez JA, Gama V, Yoshida T, Sun W, Hayes P, Leskov K, Boothman D, Matsuyama S. Gomez JA, et al. Among authors: leskov k. Biochem Soc Trans. 2007 Aug;35(Pt 4):797-801. doi: 10.1042/BST0350797. Biochem Soc Trans. 2007. PMID: 17635151 Review.

8

Recruitment of the CoREST transcription repressor complexes by Nerve Growth factor IB-like receptor (Nurr1/NR4A2) mediates silencing of HIV in microglial cells.

Ye F, Alvarez-Carbonell D, Nguyen K, Leskov K, Garcia-Mesa Y, Sreeram S, Valadkhan S, Karn J. Ye F, et al. Among authors: leskov k. PLoS Pathog. 2022 Jul 7;18(7):e1010110. doi: 10.1371/journal.ppat.1010110. eCollection 2022 Jul. PLoS Pathog. 2022. PMID: 35797416 Free PMC article.

9

Glycolysis downregulation is a hallmark of HIV-1 latency and sensitizes infected cells to oxidative stress.

Shytaj IL, Procopio FA, Tarek M, Carlon-Andres I, Tang HY, Goldman AR, Munshi M, Kumar Pal V, Forcato M, Sreeram S, Leskov K, Ye F, Lucic B, Cruz N, Ndhlovu LC, Bicciato S, Padilla-Parra S, Diaz RS, Singh A, Lusic M, Karn J, Alvarez-Carbonell D, Savarino A. Shytaj IL, et al. Among authors: leskov k. EMBO Mol Med. 2021 Aug 9;13(8):e13901. doi: 10.15252/emmm.202013901. Epub 2021 Jul 20. EMBO Mol Med. 2021. PMID: 34289240 Free PMC article.

10

Roscovitine suppresses CD4+ T cells and T cell-mediated experimental uveitis.

Zhang Z, Liu Q, Leskov KS, Wu X, Duan J, Zhang GL, Hall M, Rosenbaum JT. Zhang Z, et al. Among authors: leskov ks. PLoS One. 2013 Nov 18;8(11):e81154. doi: 10.1371/journal.pone.0081154. eCollection 2013. PLoS One. 2013. PMID: 24260551 Free PMC article.

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