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EGFR inhibition triggers an adaptive response by co-opting antiviral signaling pathways in lung cancer.
Gong K, Guo G, Panchani N, Bender ME, Gerber DE, Minna JD, Fattah F, Gao B, Peyton M, Kernstine K, Mukherjee B, Burma S, Chiang CM, Zhang S, Amod Sathe A, Xing C, Dao KH, Zhao D, Akbay EA, Habib AA. Gong K, et al. Among authors: guo g. Nat Cancer. 2020 Apr;1(4):394-409. doi: 10.1038/s43018-020-0048-0. Epub 2020 Apr 6. Nat Cancer. 2020. PMID: 33269343 Free PMC article.
Ligand-Independent EGFR Signaling.
Guo G, Gong K, Wohlfeld B, Hatanpaa KJ, Zhao D, Habib AA. Guo G, et al. Cancer Res. 2015 Sep 1;75(17):3436-41. doi: 10.1158/0008-5472.CAN-15-0989. Epub 2015 Aug 17. Cancer Res. 2015. PMID: 26282175 Free PMC article. Review.
TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer.
Gong K, Guo G, Gerber DE, Gao B, Peyton M, Huang C, Minna JD, Hatanpaa KJ, Kernstine K, Cai L, Xie Y, Zhu H, Fattah FJ, Zhang S, Takahashi M, Mukherjee B, Burma S, Dowell J, Dao K, Papadimitrakopoulou VA, Olivas V, Bivona TG, Zhao D, Habib AA. Gong K, et al. Among authors: guo g. J Clin Invest. 2018 Jun 1;128(6):2500-2518. doi: 10.1172/JCI96148. Epub 2018 May 7. J Clin Invest. 2018. PMID: 29613856 Free PMC article.
EGFR ligand shifts the role of EGFR from oncogene to tumour suppressor in EGFR-amplified glioblastoma by suppressing invasion through BIN3 upregulation.
Guo G, Gong K, Beckley N, Zhang Y, Yang X, Chkheidze R, Hatanpaa KJ, Garzon-Muvdi T, Koduru P, Nayab A, Jenks J, Sathe AA, Liu Y, Xing C, Wu SY, Chiang CM, Mukherjee B, Burma S, Wohlfeld B, Patel T, Mickey B, Abdullah K, Youssef M, Pan E, Gerber DE, Tian S, Sarkaria JN, McBrayer SK, Zhao D, Habib AA. Guo G, et al. Nat Cell Biol. 2022 Aug;24(8):1291-1305. doi: 10.1038/s41556-022-00962-4. Epub 2022 Aug 1. Nat Cell Biol. 2022. PMID: 35915159 Free PMC article.
4,560 results