Naik H - Search Results

1

Safety, Tolerability and Pharmacokinetics of Single and Repeat Doses of Vixotrigine in Healthy Volunteers.

Naik H, Steiner DJ, Versavel M, Palmer J, Fong R. Naik H, et al. Clin Transl Sci. 2021 Jul;14(4):1272-1279. doi: 10.1111/cts.12935. Epub 2020 Dec 13. Clin Transl Sci. 2021. PMID: 33278330 Free PMC article. Clinical Trial.

2

Effects of a State- and Use-Dependent Nav1.7 Channel Blocker on Ambulatory Blood Pressure: A Randomized, Controlled Crossover Study.

Fong R, Ballow CH, Naik H, Steiner D, Palmer J, White WB. Fong R, et al. Among authors: naik h. J Clin Pharmacol. 2019 Jan;59(1):90-97. doi: 10.1002/jcph.1298. Epub 2018 Aug 24. J Clin Pharmacol. 2019. PMID: 30144099 Free PMC article. Clinical Trial.

3

Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive.

Zhao Y, Versavel M, Tidemann-Miller B, Christmann R, Naik H. Zhao Y, et al. Among authors: naik h. Clin Drug Investig. 2020 Aug;40(8):737-746. doi: 10.1007/s40261-020-00931-5. Clin Drug Investig. 2020. PMID: 32564301 Free PMC article.

4

Evaluation of the Pharmacokinetic Interaction Between the Voltage- and Use-Dependent Nav1.7 Channel Blocker Vixotrigine and Carbamazepine in Healthy Volunteers.

Dunbar J, Versavel M, Zhao Y, Tate S, Morisset V, Giblin GMP, Palmer J, Tidemann-Miller B, Naik H. Dunbar J, et al. Among authors: naik h. Clin Pharmacol Drug Dev. 2020 Jan;9(1):62-73. doi: 10.1002/cpdd.739. Epub 2019 Oct 24. Clin Pharmacol Drug Dev. 2020. PMID: 31650711 Clinical Trial.

5

Design of Phase 3 Studies Evaluating Vixotrigine for Treatment of Trigeminal Neuralgia.

Kotecha M, Cheshire WP, Finnigan H, Giblin K, Naik H, Palmer J, Tate S, Zakrzewska JM. Kotecha M, et al. Among authors: naik h. J Pain Res. 2020 Jul 1;13:1601-1609. doi: 10.2147/JPR.S247182. eCollection 2020. J Pain Res. 2020. PMID: 32669869 Free PMC article.

6

Discovery of Vixotrigine: A Novel Use-Dependent Sodium Channel Blocker for the Treatment of Trigeminal Neuralgia.

Witty DR, Alvaro G, Derjean D, Giblin GMP, Gunn K, Large C, Macpherson DT, Morisset V, Owen D, Palmer J, Rugiero F, Tate S, Hinckley CA, Naik H. Witty DR, et al. Among authors: naik h. ACS Med Chem Lett. 2020 Jul 16;11(9):1678-1687. doi: 10.1021/acsmedchemlett.0c00263. eCollection 2020 Sep 10. ACS Med Chem Lett. 2020. PMID: 32945812 Free PMC article.

7

Evaluation of the Effect of Uridine Diphosphate-Glucuronosyltransferases (UGT) Inhibition by Valproic Acid on Vixotrigine Pharmacokinetics in Healthy Volunteers.

Zhao Y, Kotecha M, Finnigan H, Serenko M, Naik H. Zhao Y, et al. Among authors: naik h. Clin Drug Investig. 2022 Oct;42(10):829-837. doi: 10.1007/s40261-022-01194-y. Epub 2022 Aug 31. Clin Drug Investig. 2022. PMID: 36045316 Clinical Trial.

8

Population Pharmacokinetics of Vixotrigine in Healthy Volunteers and Subjects with Trigeminal Neuralgia, Painful Lumbosacral Radiculopathy and Erythromelalgia.

Naik H, Zhao Y, Forrestal F, Cleall S, Bockbrader H, Chapel S. Naik H, et al. Eur J Drug Metab Pharmacokinet. 2021 May;46(3):395-404. doi: 10.1007/s13318-021-00678-0. Eur J Drug Metab Pharmacokinet. 2021. PMID: 33782834

9

Characterization of Vixotrigine, a Broad-Spectrum Voltage-Gated Sodium Channel Blocker.

Hinckley CA, Kuryshev Y, Sers A, Barre A, Buisson B, Naik H, Hajos M. Hinckley CA, et al. Among authors: naik h. Mol Pharmacol. 2021 Jan;99(1):49-59. doi: 10.1124/molpharm.120.000079. Mol Pharmacol. 2021. PMID: 33298520

10

Safety, tolerability, pharmacokinetics, and pharmacodynamic properties of the GPR40 agonist TAK-875: results from a double-blind, placebo-controlled single oral dose rising study in healthy volunteers.

Naik H, Vakilynejad M, Wu J, Viswanathan P, Dote N, Higuchi T, Leifke E. Naik H, et al. J Clin Pharmacol. 2012 Jul;52(7):1007-16. doi: 10.1177/0091270011409230. Epub 2011 May 24. J Clin Pharmacol. 2012. PMID: 21610201 Clinical Trial.

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