Walsh SJ - Search Results

1

Site-selective modification strategies in antibody-drug conjugates.

Walsh SJ , Bargh JD , Dannheim FM , Hanby AR , Seki H , Counsell AJ , Ou X , Fowler E , Ashman N , Takada Y , Isidro-Llobet A , Parker JS , Carroll JS , Spring DR . Walsh SJ , et al. Chem Soc Rev. 2021 Jan 21;50(2):1305-1353. doi: 10.1039/d0cs00310g. Epub 2020 Dec 8. Chem Soc Rev. 2021. PMID: 33290462 Review.

2

Protein modification via alkyne hydrosilylation using a substoichiometric amount of ruthenium(ii) catalyst.

Kwan TT, Boutureira O, Frye EC, Walsh SJ, Gupta MK, Wallace S, Wu Y, Zhang F, Sore HF, Galloway WRJD, Chin JW, Welch M, Bernardes GJL, Spring DR. Kwan TT, et al. Among authors: walsh sj. Chem Sci. 2017 May 1;8(5):3871-3878. doi: 10.1039/c6sc05313k. Epub 2017 Mar 14. Chem Sci. 2017. PMID: 28966779 Free PMC article.

3

Toolbox of Diverse Linkers for Navigating the Cellular Efficacy Landscape of Stapled Peptides.

Wu Y, Kaur A, Fowler E, Wiedmann MM, Young R, Galloway WRJD, Olsen L, Sore HF, Chattopadhyay A, Kwan TT, Xu W, Walsh SJ, de Andrade P, Janecek M, Arumugam S, Itzhaki LS, Lau YH, Spring DR. Wu Y, et al. Among authors: walsh sj. ACS Chem Biol. 2019 Mar 15;14(3):526-533. doi: 10.1021/acschembio.9b00063. Epub 2019 Feb 7. ACS Chem Biol. 2019. PMID: 30702850

4

A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Chem Sci. 2018 Nov 9;10(3):694-700. doi: 10.1039/c8sc04645j. eCollection 2019 Jan 21. Chem Sci. 2018. PMID: 30774870 Free PMC article.

5

Correction: A general approach for the site-selective modification of native proteins, enabling the generation of stable and functional antibody-drug conjugates.

Walsh SJ, Omarjee S, Galloway WRJD, Kwan TT, Sore HF, Parker JS, Hyvönen M, Carroll JS, Spring DR. Walsh SJ, et al. Chem Sci. 2018 Dec 13;10(2):633-634. doi: 10.1039/c8sc90248h. eCollection 2019 Jan 14. Chem Sci. 2018. PMID: 30778404 Free PMC article.

6

Targeted covalent inhibitors of MDM2 using electrophile-bearing stapled peptides.

Charoenpattarapreeda J, Tan YS, Iegre J, Walsh SJ, Fowler E, Eapen RS, Wu Y, Sore HF, Verma CS, Itzhaki L, Spring DR. Charoenpattarapreeda J, et al. Among authors: walsh sj. Chem Commun (Camb). 2019 Jul 14;55(55):7914-7917. doi: 10.1039/c9cc04022f. Epub 2019 Jun 21. Chem Commun (Camb). 2019. PMID: 31225847

7

Macrocyclisation and functionalisation of unprotected peptides via divinyltriazine cysteine stapling.

Robertson NS , Walsh SJ , Fowler E , Yoshida M , Rowe SM , Wu Y , Sore HF , Parker JS , Spring DR . Robertson NS , et al. Among authors: walsh sj. Chem Commun (Camb). 2019 Aug 7;55(64):9499-9502. doi: 10.1039/c9cc05042f. Chem Commun (Camb). 2019. PMID: 31328756

8

Total synthesis and biological evaluation of simplified aplyronine analogues as synthetically tractable anticancer agents.

Pettigrew TR, Porter RJ, Walsh SJ, Housden MP, Lam NYS, Carroll JS, Parker JS, Spring DR, Paterson I. Pettigrew TR, et al. Among authors: walsh sj. Chem Commun (Camb). 2020 Feb 4;56(10):1529-1532. doi: 10.1039/c9cc09050a. Epub 2020 Jan 10. Chem Commun (Camb). 2020. PMID: 31922172

9

General dual functionalisation of biomacromolecules via a cysteine bridging strategy.

Walsh SJ, Iegre J, Seki H, Bargh JD, Sore HF, Parker JS, Carroll JS, Spring DR. Walsh SJ, et al. Org Biomol Chem. 2020 Jun 10;18(22):4224-4230. doi: 10.1039/d0ob00907e. Org Biomol Chem. 2020. PMID: 32432632

10

Efficient and selective antibody modification with functionalised divinyltriazines.

Counsell AJ, Walsh SJ, Robertson NS, Sore HF, Spring DR. Counsell AJ, et al. Among authors: walsh sj. Org Biomol Chem. 2020 Jul 1;18(25):4739-4743. doi: 10.1039/d0ob01002b. Org Biomol Chem. 2020. PMID: 32608446

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