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Minimal information for Chemosensitivity assays (MICHA): A next-generation pipeline to enable the FAIRification of drug screening experiments.
Tanoli Z, Aldahdooh J, Alam F, Wang Y, Seemab U, Fratelli M, Pavlis P, Hajduch M, Bietrix F, Gribbon P, Zaliani A, Hall MD, Shen M, Brimacombe K, Kulesskiy E, Saarela J, Wennerberg K, Vähä-Koskela M, Tang J. Tanoli Z, et al. Among authors: shen m. bioRxiv [Preprint]. 2021 Jun 12:2020.12.03.409409. doi: 10.1101/2020.12.03.409409. bioRxiv. 2021. Update in: Brief Bioinform. 2022 Jan 17;23(1):bbab350. doi: 10.1093/bib/bbab350 PMID: 33300000 Free PMC article. Updated. Preprint.
The SARS-CoV-2 cytopathic effect is blocked with autophagy modulators.
Gorshkov K, Chen CZ, Bostwick R, Rasmussen L, Xu M, Pradhan M, Tran BN, Zhu W, Shamim K, Huang W, Hu X, Shen M, Klumpp-Thomas C, Itkin Z, Shinn P, Simeonov A, Michael S, Hall MD, Lo DC, Zheng W. Gorshkov K, et al. Among authors: shen m. bioRxiv [Preprint]. 2020 May 28:2020.05.16.091520. doi: 10.1101/2020.05.16.091520. bioRxiv. 2020. Update in: ACS Infect Dis. 2021 Jun 11;7(6):1389-1408. doi: 10.1021/acsinfecdis.0c00349 PMID: 32511355 Free PMC article. Updated. Preprint.
An OpenData portal to share COVID-19 drug repurposing data in real time.
Brimacombe KR, Zhao T, Eastman RT, Hu X, Wang K, Backus M, Baljinnyam B, Chen CZ, Chen L, Eicher T, Ferrer M, Fu Y, Gorshkov K, Guo H, Hanson QM, Itkin Z, Kales SC, Klumpp-Thomas C, Lee EM, Michael S, Mierzwa T, Patt A, Pradhan M, Renn A, Shinn P, Shrimp JH, Viraktamath A, Wilson KM, Xu M, Zakharov AV, Zhu W, Zheng W, Simeonov A, Mathé EA, Lo DC, Hall MD, Shen M. Brimacombe KR, et al. Among authors: shen m. bioRxiv [Preprint]. 2020 Jun 5:2020.06.04.135046. doi: 10.1101/2020.06.04.135046. bioRxiv. 2020. PMID: 32511420 Free PMC article. Preprint.
Targeting ACE2-RBD interaction as a platform for COVID19 therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay.
Hanson QM, Wilson KM, Shen M, Itkin Z, Eastman RT, Shinn P, Hall MD. Hanson QM, et al. Among authors: shen m. bioRxiv [Preprint]. 2020 Jun 16:2020.06.16.154708. doi: 10.1101/2020.06.16.154708. bioRxiv. 2020. Update in: ACS Pharmacol Transl Sci. 2020 Nov 17;3(6):1352-1360. doi: 10.1021/acsptsci.0c00161 PMID: 32577632 Free PMC article. Updated. Preprint.
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19.
Shrimp JH, Kales SC, Sanderson PE, Simeonov A, Shen M, Hall MD. Shrimp JH, et al. Among authors: shen m. bioRxiv [Preprint]. 2020 Aug 6:2020.06.23.167544. doi: 10.1101/2020.06.23.167544. bioRxiv. 2020. Update in: ACS Pharmacol Transl Sci. 2020 Sep 07;3(5):997-1007. doi: 10.1021/acsptsci.0c00106 PMID: 32596694 Free PMC article. Updated. Preprint.
Drug Repurposing Screen for Compounds Inhibiting the Cytopathic Effect of SARS-CoV-2.
Chen CZ, Shinn P, Itkin Z, Eastman RT, Bostwick R, Rasmussen L, Huang R, Shen M, Hu X, Wilson KM, Brooks B, Guo H, Zhao T, Klump-Thomas C, Simeonov A, Michael SG, Lo DC, Hall MD, Zheng W. Chen CZ, et al. Among authors: shen m. bioRxiv [Preprint]. 2020 Aug 18:2020.08.18.255877. doi: 10.1101/2020.08.18.255877. bioRxiv. 2020. Update in: Front Pharmacol. 2021 Jan 25;11:592737. doi: 10.3389/fphar.2020.592737 PMID: 32839771 Free PMC article. Updated. Preprint.
6,980 results