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Severe hypertriglyceridemia is primarily polygenic.
Dron JS, Wang J, Cao H, McIntyre AD, Iacocca MA, Menard JR, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Dron JS, et al. Among authors: pullinger cr. J Clin Lipidol. 2019 Jan-Feb;13(1):80-88. doi: 10.1016/j.jacl.2018.10.006. Epub 2018 Oct 24. J Clin Lipidol. 2019. PMID: 30466821 Free article.
Loss-of-Function CREB3L3 Variants in Patients With Severe Hypertriglyceridemia.
Dron JS, Dilliott AA, Lawson A, McIntyre AD, Davis BD, Wang J, Cao H, Movsesyan I, Malloy MJ, Pullinger CR, Kane JP, Hegele RA. Dron JS, et al. Among authors: pullinger cr. Arterioscler Thromb Vasc Biol. 2020 Aug;40(8):1935-1941. doi: 10.1161/ATVBAHA.120.314168. Epub 2020 Jun 25. Arterioscler Thromb Vasc Biol. 2020. PMID: 32580631 Free article.
Aberrant hetero-disulfide bond formation by the hypertriglyceridemia-associated p.Gly185Cys APOA5 variant (rs2075291).
Sharma V, Witkowski A, Witkowska HE, Dykstra A, Simonsen JB, Nelbach L, Beckstead JA, Pullinger CR, Kane JP, Malloy MJ, Watson G, Forte TM, Ryan RO. Sharma V, et al. Among authors: pullinger cr. Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2254-60. doi: 10.1161/ATVBAHA.114.304027. Epub 2014 Aug 14. Arterioscler Thromb Vasc Biol. 2014. PMID: 25127531 Free PMC article.
140 results