miR-223-3p promotes autoreactive Th17 cell responses in experimental autoimmune uveitis (EAU) by inhibiting transcription factor FOXO3 expression.
Wei Y, Chen S, Sun D, Li X, Wei R, Li X, Nian H.
Wei Y, et al. Among authors: nian h.
FASEB J. 2019 Dec;33(12):13951-13965. doi: 10.1096/fj.201901446R. Epub 2019 Oct 23.
FASEB J. 2019.
PMID: 31645142
Pathogenic T helper (T(h))17 cells are key mediators of autoimmune diseases such as uveitis and its animal model, experimental autoimmune uveitis (EAU). ...Thus, our results reveal an important role for miR-223-3p in autoreactive T(h)17 cell responses and suggest a …
Pathogenic T helper (T(h))17 cells are key mediators of autoimmune diseases such as uveitis and its animal model, experimental autoim …