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High PARP-1 expression predicts poor survival in acute myeloid leukemia and PARP-1 inhibitor and SAHA-bendamustine hybrid inhibitor combination treatment synergistically enhances anti-tumor effects.
Li X, Li C, Jin J, Wang J, Huang J, Ma Z, Huang X, He X, Zhou Y, Xu Y, Yu M, Huang S, Yan X, Li F, Pan J, Wang Y, Yu Y, Jin J. Li X, et al. EBioMedicine. 2018 Dec;38:47-56. doi: 10.1016/j.ebiom.2018.11.025. Epub 2018 Nov 22. EBioMedicine. 2018. PMID: 30472087 Free PMC article.
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC.
Li C, Dong L, Su R, Bi Y, Qing Y, Deng X, Zhou Y, Hu C, Yu M, Huang H, Jiang X, Li X, He X, Zou D, Shen C, Han L, Sun M, Skibbe J, Ferchen K, Qin X, Weng H, Huang H, Song C, Chen J, Jin J. Li C, et al. Haematologica. 2020 Jan;105(1):148-160. doi: 10.3324/haematol.2018.208835. Epub 2019 Apr 11. Haematologica. 2020. PMID: 30975912 Free PMC article.
945 results