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SCRT1 is a novel beta cell transcription factor with insulin regulatory properties.
Chriett S, Lindqvist A, Shcherbina L, Edlund A, Abels M, Asplund O, Martínez López JA, Ottosson-Laakso E, Hatem G, Prasad RB, Groop L, Eliasson L, Hansson O, Wierup N. Chriett S, et al. Among authors: groop l. Mol Cell Endocrinol. 2021 Feb 5;521:111107. doi: 10.1016/j.mce.2020.111107. Epub 2020 Dec 10. Mol Cell Endocrinol. 2021. PMID: 33309639
Ghrelin suppresses insulin secretion in human islets and type 2 diabetes patients have diminished islet ghrelin cell number and lower plasma ghrelin levels.
Lindqvist A, Shcherbina L, Prasad RB, Miskelly MG, Abels M, Martínez-Lopéz JA, Fred RG, Nergård BJ, Hedenbro J, Groop L, Hjerling-Leffler J, Wierup N. Lindqvist A, et al. Among authors: groop l. Mol Cell Endocrinol. 2020 Jul 1;511:110835. doi: 10.1016/j.mce.2020.110835. Epub 2020 May 3. Mol Cell Endocrinol. 2020. PMID: 32371087 Free article.
Precision medicine in type 2 diabetes.
Prasad RB, Groop L. Prasad RB, et al. Among authors: groop l. J Intern Med. 2019 Jan;285(1):40-48. doi: 10.1111/joim.12859. Epub 2018 Dec 7. J Intern Med. 2019. PMID: 30403316 Free article. Review.
A common variant upstream of the PAX6 gene influences islet function in man.
Ahlqvist E, Turrini F, Lang ST, Taneera J, Zhou Y, Almgren P, Hansson O, Isomaa B, Tuomi T, Eriksson K, Eriksson JG, Lyssenko V, Groop L. Ahlqvist E, et al. Among authors: groop l. Diabetologia. 2012 Jan;55(1):94-104. doi: 10.1007/s00125-011-2300-8. Epub 2011 Sep 16. Diabetologia. 2012. PMID: 21922321
936 results