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Discovery of a Potent Adenine-Benzyltriazolo-Pleuromutilin Conjugate with Pronounced Antibacterial Activity against MRSA.
J Med Chem. 2020 Dec 24;63(24):15693-15708. doi: 10.1021/acs.jmedchem.0c01328. Epub 2020 Dec 16.
J Med Chem. 2020.
PMID: 33325700
Hit-to-Lead Identification and Validation of a Triaromatic Pleuromutilin Antibiotic Candidate.
Heidtmann CV, Fejer AR, Stærk K, Pedersen M, Asmussen MG, Hertz FB, Prabhala BK, Frimodt-Møller N, Klitgaard JK, Andersen TE, Nielsen CU, Nielsen P.
Heidtmann CV, et al.
J Med Chem. 2024 Mar 14;67(5):3692-3710. doi: 10.1021/acs.jmedchem.3c02153. Epub 2024 Feb 22.
J Med Chem. 2024.
PMID: 38385364
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Structure-Activity Relationship Studies and Optimization of 4-Hydroxypyridones as GPR84 Agonists.
Ieremias L, Kaspersen MH, Manandhar A, Schultz-Knudsen K, Vrettou CI, Pokhrel R, Heidtmann CV, Jenkins L, Kanellou C, Marsango S, Li Y, Bräuner-Osborne H, Rexen Ulven E, Milligan G, Ulven T.
Ieremias L, et al. Among authors: heidtmann cv.
J Med Chem. 2024 Mar 14;67(5):3542-3570. doi: 10.1021/acs.jmedchem.3c01923. Epub 2024 Feb 21.
J Med Chem. 2024.
PMID: 38381650
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The infectious capacity of Enterococcus faecalis, Staphylococcus aureus, and Staphylococcus saprophyticus in a porcine model of urinary tract infection.
Stærk K, Heidtmann CV, Hjelmager JS, Ewald JD, Nielsen CU, Nielsen P, Andersen TE.
Stærk K, et al. Among authors: heidtmann cv.
APMIS. 2024 Nov;132(11):807-813. doi: 10.1111/apm.13469. Epub 2024 Sep 18.
APMIS. 2024.
PMID: 39295304
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