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Page 1
Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase.
Mickolajczyk KJ, Shelton PMM, Grasso M, Cao X, Warrington SE, Aher A, Liu S, Kapoor TM. Mickolajczyk KJ, et al. Among authors: kapoor tm. Biophys J. 2021 Mar 16;120(6):1020-1030. doi: 10.1016/j.bpj.2020.11.2276. Epub 2020 Dec 17. Biophys J. 2021. PMID: 33340543 Free PMC article.
Structural basis for helicase-polymerase coupling in the SARS-CoV-2 replication-transcription complex.
Chen J, Malone B, Llewellyn E, Grasso M, Shelton PMM, Olinares PDB, Maruthi K, Eng E, Vatandaslar H, Chait BT, Kapoor T, Darst SA, Campbell EA. Chen J, et al. bioRxiv [Preprint]. 2020 Jul 13:2020.07.08.194084. doi: 10.1101/2020.07.08.194084. bioRxiv. 2020. Update in: Cell. 2020 Sep 17;182(6):1560-1573.e13. doi: 10.1016/j.cell.2020.07.033 PMID: 32676607 Free PMC article. Updated. Preprint.
Long-range intramolecular allostery and regulation in the dynein-like AAA protein Mdn1.
Mickolajczyk KJ, Olinares PDB, Niu Y, Chen N, Warrington SE, Sasaki Y, Walz T, Chait BT, Kapoor TM. Mickolajczyk KJ, et al. Among authors: kapoor tm. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18459-18469. doi: 10.1073/pnas.2002792117. Epub 2020 Jul 21. Proc Natl Acad Sci U S A. 2020. PMID: 32694211 Free PMC article.
A chemical genetics approach to examine the functions of AAA proteins.
Cupido T, Jones NH, Grasso MJ, Pisa R, Kapoor TM. Cupido T, et al. Among authors: kapoor tm. Nat Struct Mol Biol. 2021 Apr;28(4):388-397. doi: 10.1038/s41594-021-00575-9. Epub 2021 Mar 29. Nat Struct Mol Biol. 2021. PMID: 33782614 Free PMC article.
Targeting allostery in the Dynein motor domain with small molecule inhibitors.
Santarossa CC, Mickolajczyk KJ, Steinman JB, Urnavicius L, Chen N, Hirata Y, Fukase Y, Coudray N, Ekiert DC, Bhabha G, Kapoor TM. Santarossa CC, et al. Among authors: kapoor tm. Cell Chem Biol. 2021 Oct 21;28(10):1460-1473.e15. doi: 10.1016/j.chembiol.2021.04.024. Epub 2021 May 19. Cell Chem Biol. 2021. PMID: 34015309 Free PMC article.
A wrench in the motor.
Shelton PMM, Kapoor TM. Shelton PMM, et al. Among authors: kapoor tm. Nat Chem Biol. 2022 Apr;18(4):355-356. doi: 10.1038/s41589-021-00897-1. Nat Chem Biol. 2022. PMID: 34857957 No abstract available.
143 results