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Synthetic human ABCB4 mRNA therapy rescues severe liver disease phenotype in a BALB/c.Abcb4-/- mouse model of PFIC3.
Wei G, Cao J, Huang P, An P, Badlani D, Vaid KA, Zhao S, Wang DQ, Zhuo J, Yin L, Frassetto A, Markel A, Presnyak V, Gandham S, Hua S, Lukacs C, Finn PF, Giangrande PH, Martini PGV, Popov YV. Wei G, et al. Among authors: zhao s. J Hepatol. 2021 Jun;74(6):1416-1428. doi: 10.1016/j.jhep.2020.12.010. Epub 2020 Dec 17. J Hepatol. 2021. PMID: 33340584 Free PMC article.
Comparison of murine steatohepatitis models identifies a dietary intervention with robust fibrosis, ductular reaction, and rapid progression to cirrhosis and cancer.
Wei G, An P, Vaid KA, Nasser I, Huang P, Tan L, Zhao S, Schuppan D, Popov YV. Wei G, et al. Among authors: zhao s. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G174-G188. doi: 10.1152/ajpgi.00041.2019. Epub 2019 Oct 21. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 31630534 Free PMC article.
ASK1/ p38 axis inhibition blocks the release of mitochondrial "danger signals" from hepatocytes and suppresses progression to cirrhosis and liver cancer.
Peng Z, Wei G, Huang P, Matta H, Gao W, An P, Zhao S, Lin Y, Tan L, Vaid K, Skelton-Badlani D, Nasser I, Budas G, Lopez D, Li L, Breckenridge D, Myers R, McHutchison J, Kuang M, Popov YV. Peng Z, et al. Among authors: zhao s. Hepatology. 2024 Aug 1;80(2):346-362. doi: 10.1097/HEP.0000000000000801. Epub 2024 Feb 20. Hepatology. 2024. PMID: 38377458
Transposon-based oncogene integration in Abcb4(Mdr2)-/- mice recapitulates high susceptibility to cholangiocarcinoma in primary sclerosing cholangitis.
Huang P, Wei G, Kirkpatrick JD, Lin Y, Tan L, Matta H, Nasser I, Huang M, Chen L, Petitjean M, Skelton-Badlani D, Gao W, Vaid K, Zhao S, Lugovskoy A, Alenzi M, Chen X, Gores GJ, Popov YV. Huang P, et al. Among authors: zhao s. J Hepatol. 2025 Jan;82(1):84-96. doi: 10.1016/j.jhep.2024.07.016. Epub 2024 Jul 30. J Hepatol. 2025. PMID: 39089631 Free article.
Development of and Testing Novel Questionnaires Assessing Palliative Care-Related Knowledge, Attitudes, and Confidence Among Home Healthcare Clinicians, Patients, and Caregivers.
Chastain AM, Shang J, Murali KP, King L, Ogunlusi C, Zhao S, Kang JA, Zhao Y, Dualeh K, McDonald MV. Chastain AM, et al. Among authors: zhao s. Home Healthc Now. 2025 Jan-Feb 01;43(1):21-31. doi: 10.1097/NHH.0000000000001316. Epub 2025 Jan 7. Home Healthc Now. 2025. PMID: 39763039
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