Simeone X - Search Results

1

Allosteric Modulation of GABA_A Receptors in Rat Basolateral Amygdala Blocks Stress-Enhanced Reacquisition of Nicotine Self-Administration.

Sharp BM, Jiang Q, Simeone X, Scholze P. Sharp BM, et al. Among authors: simeone x. ACS Pharmacol Transl Sci. 2020 Oct 19;3(6):1158-1164. doi: 10.1021/acsptsci.0c00111. eCollection 2020 Dec 11. ACS Pharmacol Transl Sci. 2020. PMID: 33344894 Free PMC article.

2

Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes.

David R, Ciuraszkiewicz A, Simeone X, Orr-Urtreger A, Papke RL, McIntosh JM, Huck S, Scholze P. David R, et al. Among authors: simeone x. Eur J Neurosci. 2010 Mar;31(6):978-93. doi: 10.1111/j.1460-9568.2010.07133.x. Epub 2010 Mar 3. Eur J Neurosci. 2010. PMID: 20377613 Free PMC article.

3

Molecular tools for GABA_A receptors: High affinity ligands for β1-containing subtypes.

Simeone X, Siebert DCB, Bampali K, Varagic Z, Treven M, Rehman S, Pyszkowski J, Holzinger R, Steudle F, Scholze P, Mihovilovic MD, Schnürch M, Ernst M. Simeone X, et al. Sci Rep. 2017 Jul 18;7(1):5674. doi: 10.1038/s41598-017-05757-4. Sci Rep. 2017. PMID: 28720884 Free PMC article.

4

The role of the nAChR subunits α5, β2, and β4 on synaptic transmission in the mouse superior cervical ganglion.

Simeone X, Karch R, Ciuraszkiewicz A, Orr-Urtreger A, Lemmens-Gruber R, Scholze P, Huck S. Simeone X, et al. Physiol Rep. 2019 Mar;7(6):e14023. doi: 10.14814/phy2.14023. Physiol Rep. 2019. PMID: 30891952 Free PMC article.

5

GABA_A Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain-Can the Promiscuity Code Be Cracked?

Iorio MT, Vogel FD, Koniuszewski F, Scholze P, Rehman S, Simeone X, Schnürch M, Mihovilovic MD, Ernst M. Iorio MT, et al. Among authors: simeone x. Int J Mol Sci. 2020 Jan 3;21(1):334. doi: 10.3390/ijms21010334. Int J Mol Sci. 2020. PMID: 31947863 Free PMC article.

6

A novel de novo variant of GABRA1 causes increased sensitivity for GABA in vitro.

Steudle F, Rehman S, Bampali K, Simeone X, Rona Z, Hauser E, Schmidt WM, Scholze P, Ernst M. Steudle F, et al. Among authors: simeone x. Sci Rep. 2020 Feb 11;10(1):2379. doi: 10.1038/s41598-020-59323-6. Sci Rep. 2020. PMID: 32047208 Free PMC article.

7

A Benzodiazepine Ligand with Improved GABA_A Receptor α5-Subunit Selectivity Driven by Interactions with Loop C.

Simeone X, Koniuszewski F, Müllegger M, Smetka A, Steudle F, Puthenkalam R, Ernst M, Scholze P. Simeone X, et al. Mol Pharmacol. 2021 Jan;99(1):39-48. doi: 10.1124/molpharm.120.000067. Epub 2020 Dec 2. Mol Pharmacol. 2021. PMID: 33268553

8

Novel alpha6 preferring GABA-A receptor ligands based on loreclezole.

Simeone X, Ernst M, Seidel T, Heider J, Enz D, Monticelli S, Vogel FD, Koniuszewski F, Langer T, Scholze P, Pace V, Miele M. Simeone X, et al. Eur J Med Chem. 2022 Dec 15;244:114780. doi: 10.1016/j.ejmech.2022.114780. Epub 2022 Sep 17. Eur J Med Chem. 2022. PMID: 36279694

9

Defined concatenated α6α1β3γ2 GABA_A receptor constructs reveal dual action of pyrazoloquinolinone allosteric modulators.

Simeone X, Iorio MT, Siebert DCB, Rehman S, Schnürch M, Mihovilovic MD, Ernst M. Simeone X, et al. Bioorg Med Chem. 2019 Jul 15;27(14):3167-3178. doi: 10.1016/j.bmc.2019.06.006. Epub 2019 Jun 5. Bioorg Med Chem. 2019. PMID: 31186146

10

Structural Studies of GABAA Receptor Binding Sites: Which Experimental Structure Tells us What?

Puthenkalam R, Hieckel M, Simeone X, Suwattanasophon C, Feldbauer RV, Ecker GF, Ernst M. Puthenkalam R, et al. Among authors: simeone x. Front Mol Neurosci. 2016 Jun 16;9:44. doi: 10.3389/fnmol.2016.00044. eCollection 2016. Front Mol Neurosci. 2016. PMID: 27378845 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

14 results

Search Page

Filters