Arndt KT - Search Results

1

Sustained mTORC1 activity during palbociclib-induced growth arrest triggers senescence in ER+ breast cancer cells.

Maskey RS, Wang F, Lehman E, Wang Y, Emmanuel N, Zhong W, Jin G, Abraham RT, Arndt KT, Myers JS, Mazurek A. Maskey RS, et al. Among authors: arndt kt. Cell Cycle. 2021 Jan;20(1):65-80. doi: 10.1080/15384101.2020.1859195. Epub 2020 Dec 28. Cell Cycle. 2021. PMID: 33356791 Free PMC article.

2

Molecular Pathways: Targeting the Cyclin D-CDK4/6 Axis for Cancer Treatment.

VanArsdale T, Boshoff C, Arndt KT, Abraham RT. VanArsdale T, et al. Among authors: arndt kt. Clin Cancer Res. 2015 Jul 1;21(13):2905-10. doi: 10.1158/1078-0432.CCR-14-0816. Epub 2015 May 4. Clin Cancer Res. 2015. PMID: 25941111 Review.

3

Tumor cells chronically treated with a trastuzumab-maytansinoid antibody-drug conjugate develop varied resistance mechanisms but respond to alternate treatments.

Loganzo F, Tan X, Sung M, Jin G, Myers JS, Melamud E, Wang F, Diesl V, Follettie MT, Musto S, Lam MH, Hu W, Charati MB, Khandke K, Kim KS, Cinque M, Lucas J, Graziani E, Maderna A, O'Donnell CJ, Arndt KT, Gerber HP. Loganzo F, et al. Among authors: arndt kt. Mol Cancer Ther. 2015 Apr;14(4):952-63. doi: 10.1158/1535-7163.MCT-14-0862. Epub 2015 Feb 2. Mol Cancer Ther. 2015. PMID: 25646013

4

Specific IKKbeta inhibitor IV blocks Streptonigrin-induced NF-kappaB activity and potentiates its cytotoxic effect on cancer cells.

Gavriil M, Tsao CC, Mandiyan S, Arndt K, Abraham R, Zhang Y. Gavriil M, et al. Mol Carcinog. 2009 Aug;48(8):678-84. doi: 10.1002/mc.20550. Mol Carcinog. 2009. PMID: 19444813

5

PINCER: improved CRISPR/Cas9 screening by efficient cleavage at conserved residues.

Veeneman B, Gao Y, Grant J, Fruhling D, Ahn J, Bosbach B, Bienkowska J, Follettie M, Arndt K, Myers J, Zhong W. Veeneman B, et al. Nucleic Acids Res. 2020 Sep 25;48(17):9462-9477. doi: 10.1093/nar/gkaa645. Nucleic Acids Res. 2020. PMID: 32821942 Free PMC article.

6

IkappaBalpha kinase inhibitor IKI-1 conferred tumor necrosis factor alpha sensitivity to pancreatic cancer cells and a xenograft tumor model.

Zhang Y, Gavriil M, Lucas J, Mandiyan S, Follettie M, Diesl V, Sum FW, Powell D, Haney S, Abraham R, Arndt K. Zhang Y, et al. Cancer Res. 2008 Nov 15;68(22):9519-24. doi: 10.1158/0008-5472.CAN-08-1549. Cancer Res. 2008. PMID: 19010928

7

Epigenetic reprogramming by tumor-derived EZH2 gain-of-function mutations promotes aggressive 3D cell morphologies and enhances melanoma tumor growth.

Barsotti AM, Ryskin M, Zhong W, Zhang WG, Giannakou A, Loreth C, Diesl V, Follettie M, Golas J, Lee M, Nichols T, Fan C, Li G, Dann S, Fantin VR, Arndt K, Verhelle D, Rollins RA. Barsotti AM, et al. Oncotarget. 2015 Feb 20;6(5):2928-38. doi: 10.18632/oncotarget.2758. Oncotarget. 2015. PMID: 25671303 Free PMC article.

8

Cell Index Database (CELLX): a web tool for cancer precision medicine.

Ching KA, Wang K, Kan Z, Fernandez J, Zhong W, Kostrowicki J, Xie T, Zhu Z, Martini JF, Koehler M, Arndt K, Rejto P. Ching KA, et al. Pac Symp Biocomput. 2015:10-9. Pac Symp Biocomput. 2015. PMID: 25592564 Free article.

9

Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy-Resistant Breast Cancer.

Wardell SE, Ellis MJ, Alley HM, Eisele K, VanArsdale T, Dann SG, Arndt KT, Primeau T, Griffin E, Shao J, Crowder R, Lai JP, Norris JD, McDonnell DP, Li S. Wardell SE, et al. Among authors: arndt kt. Clin Cancer Res. 2015 Nov 15;21(22):5121-5130. doi: 10.1158/1078-0432.CCR-15-0360. Epub 2015 May 19. Clin Cancer Res. 2015. PMID: 25991817 Free PMC article.

10

Optimization of 4-phenylamino-3-quinolinecarbonitriles as potent inhibitors of Src kinase activity.

Boschelli DH, Ye F, Wang YD, Dutia M, Johnson SL, Wu B, Miller K, Powell DW, Yaczko D, Young M, Tischler M, Arndt K, Discafani C, Etienne C, Gibbons J, Grod J, Lucas J, Weber JM, Boschelli F. Boschelli DH, et al. J Med Chem. 2001 Nov 8;44(23):3965-77. doi: 10.1021/jm0102250. J Med Chem. 2001. PMID: 11689083

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