Dormann D - Search Results

1

Nuclear Import Receptors Directly Bind to Arginine-Rich Dipeptide Repeat Proteins and Suppress Their Pathological Interactions.

Hutten S, Usluer S, Bourgeois B, Simonetti F, Odeh HM, Fare CM, Czuppa M, Hruska-Plochan M, Hofweber M, Polymenidou M, Shorter J, Edbauer D, Madl T, Dormann D. Hutten S, et al. Among authors: dormann d. Cell Rep. 2020 Dec 22;33(12):108538. doi: 10.1016/j.celrep.2020.108538. Cell Rep. 2020. PMID: 33357437 Free PMC article.

2

ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.

Dormann D, Rodde R, Edbauer D, Bentmann E, Fischer I, Hruscha A, Than ME, Mackenzie IR, Capell A, Schmid B, Neumann M, Haass C. Dormann D, et al. EMBO J. 2010 Aug 18;29(16):2841-57. doi: 10.1038/emboj.2010.143. Epub 2010 Jul 6. EMBO J. 2010. PMID: 20606625 Free PMC article.

3

Arginine methylation next to the PY-NLS modulates Transportin binding and nuclear import of FUS.

Dormann D, Madl T, Valori CF, Bentmann E, Tahirovic S, Abou-Ajram C, Kremmer E, Ansorge O, Mackenzie IR, Neumann M, Haass C. Dormann D, et al. EMBO J. 2012 Nov 14;31(22):4258-75. doi: 10.1038/emboj.2012.261. Epub 2012 Sep 11. EMBO J. 2012. PMID: 22968170 Free PMC article.

4

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS.

Suárez-Calvet M, Neumann M, Arzberger T, Abou-Ajram C, Funk E, Hartmann H, Edbauer D, Kremmer E, Göbl C, Resch M, Bourgeois B, Madl T, Reber S, Jutzi D, Ruepp MD, Mackenzie IR, Ansorge O, Dormann D, Haass C. Suárez-Calvet M, et al. Among authors: dormann d. Acta Neuropathol. 2016 Apr;131(4):587-604. doi: 10.1007/s00401-016-1544-2. Epub 2016 Feb 19. Acta Neuropathol. 2016. PMID: 26895297 Free article.

5

hnRNPA2/B1 Function in Neurodegeneration: It's a Gain, Not a Loss.

Hutten S, Dormann D. Hutten S, et al. Among authors: dormann d. Neuron. 2016 Nov 23;92(4):672-674. doi: 10.1016/j.neuron.2016.11.014. Neuron. 2016. PMID: 27883897 Free article.

6

Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.

Khosravi B, Hartmann H, May S, Möhl C, Ederle H, Michaelsen M, Schludi MH, Dormann D, Edbauer D. Khosravi B, et al. Among authors: dormann d. Hum Mol Genet. 2017 Feb 15;26(4):790-800. doi: 10.1093/hmg/ddw432. Hum Mol Genet. 2017. PMID: 28040728 Free PMC article.

7

Phase Separation of FUS Is Suppressed by Its Nuclear Import Receptor and Arginine Methylation.

Hofweber M, Hutten S, Bourgeois B, Spreitzer E, Niedner-Boblenz A, Schifferer M, Ruepp MD, Simons M, Niessing D, Madl T, Dormann D. Hofweber M, et al. Among authors: dormann d. Cell. 2018 Apr 19;173(3):706-719.e13. doi: 10.1016/j.cell.2018.03.004. Cell. 2018. PMID: 29677514 Free article.

8

Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.

Ederle H, Funk C, Abou-Ajram C, Hutten S, Funk EBE, Kehlenbach RH, Bailer SM, Dormann D. Ederle H, et al. Among authors: dormann d. Sci Rep. 2018 May 4;8(1):7084. doi: 10.1038/s41598-018-25007-5. Sci Rep. 2018. PMID: 29728564 Free PMC article.

9

Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.

Hock EM, Maniecka Z, Hruska-Plochan M, Reber S, Laferrière F, Sahadevan M K S, Ederle H, Gittings L, Pelkmans L, Dupuis L, Lashley T, Ruepp MD, Dormann D, Polymenidou M. Hock EM, et al. Among authors: dormann d. Cell Rep. 2018 Jul 24;24(4):987-1000.e7. doi: 10.1016/j.celrep.2018.06.094. Cell Rep. 2018. PMID: 30044993 Free article.

10

Interaction modulation through arrays of clustered methyl-arginine protein modifications.

Woodsmith J, Casado-Medrano V, Benlasfer N, Eccles RL, Hutten S, Heine CL, Thormann V, Abou-Ajram C, Rocks O, Dormann D, Stelzl U. Woodsmith J, et al. Among authors: dormann d. Life Sci Alliance. 2018 Sep 21;1(5):e201800178. doi: 10.26508/lsa.201800178. eCollection 2018 Oct. Life Sci Alliance. 2018. PMID: 30456387 Free PMC article.

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