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Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart.
Wei J, Yao J, Belke D, Guo W, Zhong X, Sun B, Wang R, Paul Estillore J, Vallmitjana A, Benitez R, Hove-Madsen L, Alvarez-Lacalle E, Echebarria B, Chen SRW. Wei J, et al. Among authors: zhong x. Circ Res. 2021 Feb 19;128(4):e63-e83. doi: 10.1161/CIRCRESAHA.120.318429. Epub 2020 Dec 30. Circ Res. 2021. PMID: 33375811 Free article.
Carvedilol and its new analogs suppress arrhythmogenic store overload-induced Ca2+ release.
Zhou Q, Xiao J, Jiang D, Wang R, Vembaiyan K, Wang A, Smith CD, Xie C, Chen W, Zhang J, Tian X, Jones PP, Zhong X, Guo A, Chen H, Zhang L, Zhu W, Yang D, Li X, Chen J, Gillis AM, Duff HJ, Cheng H, Feldman AM, Song LS, Fill M, Back TG, Chen SR. Zhou Q, et al. Among authors: zhong x. Nat Med. 2011 Jul 10;17(8):1003-9. doi: 10.1038/nm.2406. Nat Med. 2011. PMID: 21743453 Free PMC article.
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
Bai Y, Jones PP, Guo J, Zhong X, Clark RB, Zhou Q, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Semeniuk L, Guo A, Song LS, Duff HJ, Chen SR. Bai Y, et al. Among authors: zhong x. Circ Res. 2013 Aug 16;113(5):517-26. doi: 10.1161/CIRCRESAHA.113.301678. Epub 2013 Jul 15. Circ Res. 2013. PMID: 23856523 Free PMC article.
The ryanodine receptor store-sensing gate controls Ca2+ waves and Ca2+-triggered arrhythmias.
Chen W, Wang R, Chen B, Zhong X, Kong H, Bai Y, Zhou Q, Xie C, Zhang J, Guo A, Tian X, Jones PP, O'Mara ML, Liu Y, Mi T, Zhang L, Bolstad J, Semeniuk L, Cheng H, Zhang J, Chen J, Tieleman DP, Gillis AM, Duff HJ, Fill M, Song LS, Chen SR. Chen W, et al. Among authors: zhong x. Nat Med. 2014 Feb;20(2):184-92. doi: 10.1038/nm.3440. Epub 2014 Jan 19. Nat Med. 2014. PMID: 24441828 Free PMC article.
7,505 results