Eizirik DL - Search Results

1

The RNA-binding profile of the splicing factor SRSF6 in immortalized human pancreatic β-cells.

Alvelos MI, Brüggemann M, Sutandy FR, Juan-Mateu J, Colli ML, Busch A, Lopes M, Castela Â, Aartsma-Rus A, König J, Zarnack K, Eizirik DL. Alvelos MI, et al. Among authors: eizirik dl. Life Sci Alliance. 2020 Dec 29;4(3):e202000825. doi: 10.26508/lsa.202000825. Print 2021 Mar. Life Sci Alliance. 2020. PMID: 33376132 Free PMC article.

2

PTPN2, a candidate gene for type 1 diabetes, modulates interferon-gamma-induced pancreatic beta-cell apoptosis.

Moore F, Colli ML, Cnop M, Esteve MI, Cardozo AK, Cunha DA, Bugliani M, Marchetti P, Eizirik DL. Moore F, et al. Among authors: eizirik dl. Diabetes. 2009 Jun;58(6):1283-91. doi: 10.2337/db08-1510. Epub 2009 Mar 31. Diabetes. 2009. PMID: 19336676 Free PMC article.

3

The role of inflammation in insulitis and beta-cell loss in type 1 diabetes.

Eizirik DL, Colli ML, Ortis F. Eizirik DL, et al. Nat Rev Endocrinol. 2009 Apr;5(4):219-26. doi: 10.1038/nrendo.2009.21. Nat Rev Endocrinol. 2009. PMID: 19352320 Review.

4

MDA5 and PTPN2, two candidate genes for type 1 diabetes, modify pancreatic beta-cell responses to the viral by-product double-stranded RNA.

Colli ML, Moore F, Gurzov EN, Ortis F, Eizirik DL. Colli ML, et al. Among authors: eizirik dl. Hum Mol Genet. 2010 Jan 1;19(1):135-46. doi: 10.1093/hmg/ddp474. Hum Mol Genet. 2010. PMID: 19825843 Free PMC article.

5

Cytokines interleukin-1beta and tumor necrosis factor-alpha regulate different transcriptional and alternative splicing networks in primary beta-cells.

Ortis F, Naamane N, Flamez D, Ladrière L, Moore F, Cunha DA, Colli ML, Thykjaer T, Thorsen K, Orntoft TF, Eizirik DL. Ortis F, et al. Among authors: eizirik dl. Diabetes. 2010 Feb;59(2):358-74. doi: 10.2337/db09-1159. Epub 2009 Nov 23. Diabetes. 2010. PMID: 19934004 Free PMC article.

6

STAT1 is a master regulator of pancreatic {beta}-cell apoptosis and islet inflammation.

Moore F, Naamane N, Colli ML, Bouckenooghe T, Ortis F, Gurzov EN, Igoillo-Esteve M, Mathieu C, Bontempi G, Thykjaer T, Ørntoft TF, Eizirik DL. Moore F, et al. Among authors: eizirik dl. J Biol Chem. 2011 Jan 14;286(2):929-41. doi: 10.1074/jbc.M110.162131. Epub 2010 Oct 27. J Biol Chem. 2011. PMID: 20980260 Free PMC article.

7

Pancreatic β-cells activate a JunB/ATF3-dependent survival pathway during inflammation.

Gurzov EN, Barthson J, Marhfour I, Ortis F, Naamane N, Igoillo-Esteve M, Gysemans C, Mathieu C, Kitajima S, Marchetti P, Ørntoft TF, Bakiri L, Wagner EF, Eizirik DL. Gurzov EN, et al. Among authors: eizirik dl. Oncogene. 2012 Mar 29;31(13):1723-32. doi: 10.1038/onc.2011.353. Epub 2011 Aug 15. Oncogene. 2012. PMID: 21841823

8

Exposure to the viral by-product dsRNA or Coxsackievirus B5 triggers pancreatic beta cell apoptosis via a Bim / Mcl-1 imbalance.

Colli ML, Nogueira TC, Allagnat F, Cunha DA, Gurzov EN, Cardozo AK, Roivainen M, Op de Beeck A, Eizirik DL. Colli ML, et al. Among authors: eizirik dl. PLoS Pathog. 2011 Sep;7(9):e1002267. doi: 10.1371/journal.ppat.1002267. Epub 2011 Sep 22. PLoS Pathog. 2011. PMID: 21977009 Free PMC article.

9

PTPN2, a candidate gene for type 1 diabetes, modulates pancreatic β-cell apoptosis via regulation of the BH3-only protein Bim.

Santin I, Moore F, Colli ML, Gurzov EN, Marselli L, Marchetti P, Eizirik DL. Santin I, et al. Among authors: eizirik dl. Diabetes. 2011 Dec;60(12):3279-88. doi: 10.2337/db11-0758. Epub 2011 Oct 7. Diabetes. 2011. PMID: 21984578 Free PMC article.

10

Use of RNA interference to investigate cytokine signal transduction in pancreatic beta cells.

Moore F, Cunha DA, Mulder H, Eizirik DL. Moore F, et al. Among authors: eizirik dl. Methods Mol Biol. 2012;820:179-94. doi: 10.1007/978-1-61779-439-1_11. Methods Mol Biol. 2012. PMID: 22131032

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