Hara T - Search Results

1

Corrigendum to "Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor" [Biochem. Biophys. Rep. 21 (2020) 100726].

Hara T, Kimura A, Miyazaki T, Tanaka H, Morimoto M, Nakai K, Soeda J. Hara T, et al. Biochem Biophys Rep. 2020 Aug 20;24:100797. doi: 10.1016/j.bbrep.2020.100797. eCollection 2020 Dec. Biochem Biophys Rep. 2020. PMID: 33381660 Free PMC article.

2

Cabozantinib inhibits AXL- and MET-dependent cancer cell migration induced by growth-arrest-specific 6 and hepatocyte growth factor.

Hara T, Kimura A, Miyazaki T, Tanaka H, Morimoto M, Nakai K, Soeda J. Hara T, et al. Biochem Biophys Rep. 2020 Jan 17;21:100726. doi: 10.1016/j.bbrep.2020.100726. eCollection 2020 Mar. Biochem Biophys Rep. 2020. PMID: 32055714 Free PMC article.

3

A selective androgen receptor modulator SARM-2f activates androgen receptor, increases lean body mass, and suppresses blood lipid levels in cynomolgus monkeys.

Morimoto M, Yamaoka M, Hara T. Morimoto M, et al. Among authors: hara t. Pharmacol Res Perspect. 2020 Feb;8(1):e00563. doi: 10.1002/prp2.563. Pharmacol Res Perspect. 2020. PMID: 32030892 Free PMC article.

4

Prevention of body weight loss and sarcopenia by a novel selective androgen receptor modulator in cancer cachexia models.

Morimoto M, Aikawa K, Hara T, Yamaoka M. Morimoto M, et al. Among authors: hara t. Oncol Lett. 2017 Dec;14(6):8066-8071. doi: 10.3892/ol.2017.7200. Epub 2017 Oct 17. Oncol Lett. 2017. PMID: 29344250 Free PMC article.

5

Amelioration of sexual behavior and motor activity deficits in a castrated rodent model with a selective androgen receptor modulator SARM-2f.

Morimoto M, Amano Y, Oka M, Harada A, Fujita H, Hikichi Y, Tozawa R, Yamaoka M, Hara T. Morimoto M, et al. Among authors: hara t. PLoS One. 2017 Dec 7;12(12):e0189480. doi: 10.1371/journal.pone.0189480. eCollection 2017. PLoS One. 2017. PMID: 29216311 Free PMC article.

6

Intratumor Heterogeneity in Primary Kidney Cancer Revealed by Metabolic Profiling of Multiple Spatially Separated Samples within Tumors.

Okegawa T, Morimoto M, Nishizawa S, Kitazawa S, Honda K, Araki H, Tamura T, Ando A, Satomi Y, Nutahara K, Hara T. Okegawa T, et al. Among authors: hara t. EBioMedicine. 2017 May;19:31-38. doi: 10.1016/j.ebiom.2017.04.009. Epub 2017 Apr 6. EBioMedicine. 2017. PMID: 28408240 Free PMC article.

7

Prolyl-tRNA synthetase inhibition promotes cell death in SK-MEL-2 cells through GCN2-ATF4 pathway activation.

Arita T, Morimoto M, Yamamoto Y, Miyashita H, Kitazawa S, Hirayama T, Sakamoto S, Miyamoto K, Adachi R, Iwatani M, Hara T. Arita T, et al. Among authors: hara t. Biochem Biophys Res Commun. 2017 Jul 8;488(4):648-654. doi: 10.1016/j.bbrc.2017.01.045. Epub 2017 Jan 11. Biochem Biophys Res Commun. 2017. PMID: 28087278

8

Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs). Part II: Optimization of 4-(pyrrolidin-1-yl)benzonitrile derivatives.

Asano M, Hitaka T, Imada T, Yamada M, Morimoto M, Shinohara H, Hara T, Yamaoka M, Santou T, Nakayama M, Imai Y, Habuka N, Yano J, Wilson K, Fujita H, Hasuoka A. Asano M, et al. Among authors: hara t. Bioorg Med Chem Lett. 2017 May 1;27(9):1897-1901. doi: 10.1016/j.bmcl.2017.03.038. Epub 2017 Mar 21. Bioorg Med Chem Lett. 2017. PMID: 28363748

9

Synthesis and biological evaluation of novel selective androgen receptor modulators (SARMs) Part III: Discovery of 4-(5-oxopyrrolidine-1-yl)benzonitrile derivative 2f as a clinical candidate.

Aikawa K, Asano M, Ono K, Habuka N, Yano J, Wilson K, Fujita H, Kandori H, Hara T, Morimoto M, Santou T, Yamaoka M, Nakayama M, Hasuoka A. Aikawa K, et al. Among authors: hara t. Bioorg Med Chem. 2017 Jul 1;25(13):3330-3349. doi: 10.1016/j.bmc.2017.04.018. Epub 2017 Apr 13. Bioorg Med Chem. 2017. PMID: 28454849

10

[Pharmacological properties and clinical outcomes of the anti-cancer drug, cabozantinib (CABOMETYX^®)].

Osaka T, Yamaguchi N, Hara T. Osaka T, et al. Among authors: hara t. Nihon Yakurigaku Zasshi. 2021;156(5):303-311. doi: 10.1254/fpj.21045. Nihon Yakurigaku Zasshi. 2021. PMID: 34470936 Japanese.

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